Karow A, Verthein U, Krausz M, Schafer I
Department of Psychiatry und Psychotherapy, University Hospital Hamburg Eppendorf, Hamburg, Germany.
Eur Addict Res. 2008;14(1):38-46. doi: 10.1159/000110409. Epub 2008 Jan 7.
The purpose of this study was to investigate the association of the current status and longitudinal changes in different clinical and social variables with quality of life (QOL) in opiate addiction. Our hypotheses were that drug use, comorbid personality disorders and social problems are associated with worse QOL.
107 participants with long-term opiate addiction were included and interviewed at entry with the Europ-ASI and the PDQ-R. QOL (SF-36) and changes in different domains of the Europ-ASI were assessed after 2 years.
Personality disorders, interpersonal conflicts with the family or partner and ongoing need for somatic and psychiatric treatment were significantly associated with worse subjective QOL, whereas changes in drug and alcohol use, the economic situation, legal problems and social problems with persons outside of the family showed no relevant association with QOL.
Our results provide support for an emphasis in treatment on helping clients to reduce intra- and interpersonal conflicts according to comorbid conditions and among family members and partnerships. In addition, the present data provide further support for the advantages of extended interventions in long-term opiate addiction.
本研究旨在调查不同临床和社会变量的现状及纵向变化与阿片类药物成瘾患者生活质量(QOL)之间的关联。我们的假设是,药物使用、共病的人格障碍和社会问题与较差的生活质量相关。
纳入107名长期阿片类药物成瘾者,入组时采用欧洲成瘾严重程度指数(Europ-ASI)和人格障碍问卷修订版(PDQ-R)进行访谈。2年后评估生活质量(SF-36)以及Europ-ASI不同领域的变化。
人格障碍、与家人或伴侣的人际冲突以及持续的躯体和精神治疗需求与较差的主观生活质量显著相关,而药物和酒精使用、经济状况、法律问题以及与家庭以外人员的社会问题的变化与生活质量无显著关联。
我们的结果支持在治疗中重点帮助患者根据共病情况以及在家庭成员和伴侣之间减少人际和家庭内冲突。此外,目前的数据进一步支持了长期阿片类药物成瘾延长干预措施的优势。