Denton Wayne H, Adinoff Bryon H, Lewis Daniel, Walker Robrina, Winhusen Theresa
1Florida State University, Family and Child Sciences , Tallahassee, Florida , USA.
Subst Use Misuse. 2014 Feb;49(3):326-32. doi: 10.3109/10826084.2013.840002. Epub 2013 Oct 9.
Childhood abuse and partner violence are associated with prenatal substance abuse, but the potential impact of current family discord, which reflects broader family relationships and encompasses problems less severe than violence, has had little evaluation in pregnant substance users. Using data from 196 pregnant substance users participating in a NIDA Clinical Trials Network randomized clinical trial, we examined the relationship of baseline family discord to substance use and treatment session attendance. Family discord was assessed using items from the family composite of the Addiction Severity Index. Substance use was assessed by the Substance Use Calendar and urine drug screens (UDS). Assessments were weekly for four weeks and at two- and four-month post-randomization. Women with family discord were more likely to report living with a problematic substance user, reported a higher percentage of substance use days throughout each study phase, had a greater proportion of positive UDS over the four-month study period, and attended more weeks of treatment during the first month. Specific treatment interventions targeting pregnant women with family discord may be warranted.
童年期受虐和伴侣暴力与产前药物滥用有关，但当前家庭不和的潜在影响在孕期药物使用者中几乎未得到评估，家庭不和反映了更广泛的家庭关系，且包含比暴力程度较轻的问题。利用参与美国国立药物滥用研究所临床试验网络随机临床试验的196名孕期药物使用者的数据，我们研究了基线家庭不和与药物使用及治疗疗程出勤率之间的关系。使用成瘾严重程度指数家庭综合量表中的项目评估家庭不和。通过药物使用日历和尿液药物筛查（UDS）评估药物使用情况。在四周内每周进行评估，并在随机分组后的两个月和四个月进行评估。有家庭不和的女性更有可能报告与有问题的药物使用者同住，在每个研究阶段报告的药物使用天数百分比更高，在四个月的研究期间UDS呈阳性的比例更大，并且在第一个月参加治疗的周数更多。针对有家庭不和的孕妇的特定治疗干预措施可能是必要的。
