用于癌症治疗的多壁碳纳米管-阿霉素超分子复合物
Multiwalled carbon nanotube-doxorubicin supramolecular complexes for cancer therapeutics.
作者信息
Ali-Boucetta Hanene, Al-Jamal Khuloud T, McCarthy David, Prato Maurizio, Bianco Alberto, Kostarelos Kostas
机构信息
Nanomedicine Laboratory, Centre for Drug Delivery, The School of Pharmacy, University of London, London, UK.
出版信息
Chem Commun (Camb). 2008 Jan 28(4):459-61. doi: 10.1039/b712350g. Epub 2007 Nov 14.
DOI:10.1039/b712350g
PMID:18188467
Abstract
Multiwalled carbon nanotube aqueous dispersions using block copolymers are able to form supramolecular complexes with the aromatic chromophore and anticancer agent doxorubicin via pi-pi stacking and enhance its cytotoxic activity.
摘要
使用嵌段共聚物的多壁碳纳米管水分散体能够通过π-π堆积与芳香发色团和抗癌剂阿霉素形成超分子复合物，并增强其细胞毒性活性。
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