Bender Catherine M, Engberg Sandra J, Donovan Heidi S, Cohen Susan M, Houze Martin P, Rosenzweig Margaret Q, Mallory Gail A, Dunbar-Jacob Jacqueline, Sereika Susan M
Associate professors School of Nursing, University of Pittsburgh, Pennsylvania, USA.
Oncol Nurs Forum. 2008 Jan;35(1):E1-E11. doi: 10.1188/08.ONF.E1-E11.
PURPOSE/OBJECTIVES: To identify and compare symptom clusters in individuals with chronic health problems with cancer as a comorbidity versus individuals with chronic health problems who do not have cancer as a comorbidity and to explore the effect of symptoms on their quality of life.
Secondary analysis of data from two studies. Study 1 was an investigation of the efficacy of an intervention to improve medication adherence in patients with rheumatoid arthritis (RA). Study 2 was an investigation of the efficacy of an intervention for urinary incontinence (UI) in older adults.
School of Nursing at the University of Pittsburgh.
The sample for study 1 was comprised of 639 adults with RA. The sample for study 2 was comprised of 407 adults with UI. A total of 154 (15%) subjects had a history of cancer, 56 (9%) of the subjects with RA and 98 (25%) of the subjects with UI.
Analysis of existing comorbidity and symptom data collected from both studies.
Symptom clusters, chronic disease, and cancer as a comorbidity.
Individuals with chronic health problems who have cancer may not have unique symptom clusters compared to individuals with chronic health problems who do not have cancer.
The symptom clusters experienced by the study participants may be more related to their primary chronic health problems and comorbidities.
Additional studies are needed to examine symptom clusters in cancer survivors. As individuals are living longer with the disease, a comprehensive understanding of the symptom clusters that may be unique to cancer survivors with comorbidities is critical.
目的/目标：识别并比较患有慢性健康问题且合并癌症的个体与患有慢性健康问题但未合并癌症的个体的症状群，并探讨症状对其生活质量的影响。
对两项研究的数据进行二次分析。研究1是对一项改善类风湿性关节炎（RA）患者药物依从性干预措施疗效的调查。研究2是对一项针对老年人尿失禁（UI）干预措施疗效的调查。
匹兹堡大学护理学院。
研究1的样本包括639名患有RA的成年人。研究2的样本包括407名患有UI的成年人。共有154名（15%）受试者有癌症病史，其中56名（9%）为RA受试者，98名（25%）为UI受试者。
分析从两项研究中收集的现有合并症和症状数据。
症状群、慢性病和作为合并症的癌症。
与未合并癌症的慢性健康问题个体相比，合并癌症的慢性健康问题个体可能没有独特的症状群。
研究参与者经历的症状群可能与其原发性慢性健康问题和合并症更相关。
需要进一步研究以检查癌症幸存者的症状群。随着人们带病生存时间的延长，全面了解合并症的癌症幸存者可能特有的症状群至关重要。
