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近8年期间老年人残疾的亚型。

Subtypes of disability in older persons over the course of nearly 8 years.

作者信息

Gill Thomas M, Guo Zhenchao, Allore Heather G

机构信息

Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06504, USA.

出版信息

J Am Geriatr Soc. 2008 Mar;56(3):436-43. doi: 10.1111/j.1532-5415.2007.01603.x. Epub 2008 Jan 5.

Abstract

OBJECTIVES

To characterize distinct and clinically meaningful subtypes of disability, defined based on the number and duration of disability episodes, and to determine whether the incidence of these disability subtypes differ according to age, sex, or physical frailty.

DESIGN

Prospective cohort study.

SETTING

Greater New Haven, Connecticut.

PARTICIPANTS

Seven hundred fifty-four community-living residents aged 70 and older and initially nondisabled in four essential activities of daily living.

MEASUREMENTS

Disability was assessed during monthly telephone interviews for nearly 8 years; physical frailty was assessed during comprehensive home-based assessments at 18-month intervals. The incidence of five disability subtypes was determined within the context of the 18-month intervals in participants who were nondisabled at the start of the interval: transient, short-term, long-term, recurrent, and unstable.

RESULTS

Incident disability was observed in 29.8% of the 18-month intervals. The most common subtypes were transient disability (9.7% of all intervals), defined as a single disability episode lasting only 1 month, and long-term disability (6.9%), defined as one or more disability episodes, with at least one lasting 6 or more months. Approximately one-quarter (24.7%) of all participants had two or more intervals with an incident disability subtype. Although there were no sex differences in the incidence rates for any of the subtypes, differences in rates were observed for each subtype according to age and physical frailty, with only one exception, and were especially large for long-term disability.

CONCLUSION

The mechanisms underlying the different disability subtypes may differ. Additional research is warranted to evaluate the natural history, risk factors, and prognosis of the five disability subtypes.

摘要

目的

根据残疾发作的次数和持续时间来界定不同的、具有临床意义的残疾亚型,并确定这些残疾亚型的发病率是否因年龄、性别或身体虚弱程度而异。

设计

前瞻性队列研究。

地点

康涅狄格州大纽黑文地区。

参与者

754名70岁及以上的社区居住居民,他们最初在四项基本日常生活活动中未出现残疾。

测量方法

在近8年的每月电话访谈中评估残疾情况;每18个月进行一次全面的居家评估,评估身体虚弱程度。在每个间隔期开始时未出现残疾的参与者中,确定五个残疾亚型在18个月间隔期内的发病率:短暂性、短期、长期、复发性和不稳定型。

结果

在18个月的间隔期内,29.8%的参与者出现了新发残疾。最常见的亚型是短暂性残疾(占所有间隔期的9.7%),定义为仅持续1个月 的单次残疾发作,以及长期残疾(6.9%),定义为一次或多次残疾发作,其中至少一次持续6个月或更长时间。约四分之一(24.7%)的参与者有两个或更多间隔期出现新发残疾亚型。虽然任何亚型的发病率在性别上均无差异,但根据年龄和身体虚弱程度,每个亚型的发病率存在差异,只有一个例外,长期残疾的差异尤为明显。

结论

不同残疾亚型背后的机制可能不同。有必要进行更多研究来评估这五个残疾亚型的自然史、危险因素和预后。

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