Casemiro Luciana Assirati, Gomes Martins Carlos Henrique, Pires-de-Souza Fernanda de Carvalho Panzeri, Panzeri Heitor
Dentistry College, University of Franca, Franca, SP, Brazil.
Gerodontology. 2008 Sep;25(3):187-94. doi: 10.1111/j.1741-2358.2007.00198.x. Epub 2008 Jan 13.
The purpose of this in vitro study was to evaluate the antimicrobial activity of acrylic resins containing different percentages of silver and zinc zeolite, and to assess whether the addition of zeolite alters the flexural and impact strength of the resins.
The characteristics of acrylic resins support microorganism development that can threaten the health of the dentures user.
A microwave-polymerised (Onda-Cryl) and two heat-polymerised (QC20 and Lucitone 550) acrylic resins were used. The materials were handled according to the manufacturers' instructions. Fifty rectangular-shaped specimens (8 x 10 x 4mm) were fabricated from each resin and assigned to 5 groups (n = 10) according to their percentage of Irgaguard B5000 silver-zinc zeolite (0%- control, 2.5%, 5.0%, 7.5% and 10%). Flexural strength and Izod impact strength were evaluated. The antimicrobial activity against two strains of Candida albicans and two strains of Streptococcus mutans was assessed by agar diffusion method. Data were analysed statistically by one-way anova and Tukey's test at 5% significance level.
The addition of 2.5% of Irgaguard B5000 to the materials resulted in antimicrobial activity against all strains. Flexural strength decreased significantly with the addition of 2.5% (QC20 and Lucitone 550) and 5.0% (Onda-Cryl) of Irgaguard B5000. The impact strength decreased significantly with the addition of 2.5% (Lucitone 550) and 5.0% (QC20 and Onda-Cryl) of zeolite.
The addition of silver-zinc zeolite to acrylic resins yields antimicrobial activity, but may affect negatively the mechanical properties, depending on the percentage of zeolite.
本体外研究旨在评估含有不同百分比银和锌沸石的丙烯酸树脂的抗菌活性，并评估沸石的添加是否会改变树脂的弯曲强度和冲击强度。
丙烯酸树脂的特性有利于微生物生长，这可能会威胁假牙使用者的健康。
使用一种微波聚合（Onda-Cryl）和两种热聚合（QC20和Lucitone 550）的丙烯酸树脂。材料按照制造商的说明进行处理。每种树脂制作50个矩形试样（8×10×4mm），并根据其Irgaguard B5000银锌沸石的百分比分为5组（n = 10）（0% - 对照组、2.5%、5.0%、7.5%和10%）。评估弯曲强度和艾氏冲击强度。通过琼脂扩散法评估对两种白色念珠菌菌株和两种变形链球菌菌株的抗菌活性。数据采用单因素方差分析和Tukey检验进行统计学分析，显著性水平为5%。
向材料中添加2.5%的Irgaguard B5000可产生针对所有菌株的抗菌活性。添加2.5%（QC20和Lucitone 550）和5.0%（Onda-Cryl）的Irgaguard B5000后，弯曲强度显著降低。添加2.5%（Lucitone 550）和5.0%（QC20和Onda-Cryl）的沸石后，冲击强度显著降低。
向丙烯酸树脂中添加银锌沸石可产生抗菌活性，但可能会对机械性能产生负面影响，具体取决于沸石的百分比。
