美国西班牙裔人群对癌症基因检测的认知：文化适应的作用。
Awareness of genetic testing for cancer among United States Hispanics: the role of acculturation.
作者信息
Heck Julia E, Franco Rebeca, Jurkowski Janine M, Sheinfeld Gorin Sherri
机构信息
Department of Epidemiology, Columbia University, New York, N.Y., USA.
出版信息
Community Genet. 2008;11(1):36-42. doi: 10.1159/000111638. Epub 2008 Jan 15.
BACKGROUND
The purpose of this study was to determine how acculturation affected awareness of genetic testing for cancer among Hispanic Americans.
METHODS
Subjects were 10,883 Hispanic respondents from the 2000 and 2005 National Health Interview Surveys. Acculturation was measured with language use and the length of time subjects had lived in the US. Weighted logistic regression was used to determine subjects' awareness of genetic susceptibility testing.
RESULTS
Greater use of English (adjusted odds ratio, OR = 1.25, 95% confidence interval, CI = 1.15-1.36) was associated with increased awareness of genetic testing. Residence in the US for less than 5 years (adjusted OR = 0.55, 95% CI 0.36-0.83) was associated with lower awareness of testing.
CONCLUSIONS
To better inform diverse American groups about genetic testing, intercultural variations and language skills must be taken into account.
背景
本研究的目的是确定文化适应如何影响西班牙裔美国人对癌症基因检测的认知。
方法
研究对象为来自2000年和2005年全国健康访谈调查的10883名西班牙裔受访者。文化适应程度通过语言使用情况和受访者在美国居住的时长来衡量。采用加权逻辑回归来确定研究对象对基因易感性检测的认知情况。
结果
更多地使用英语（调整后的优势比，OR = 1.25，95%置信区间，CI = 1.15 - 1.36）与基因检测认知的提高相关。在美国居住少于5年（调整后的OR = 0.55，95% CI 0.36 - 0.83）与检测认知较低相关。
结论
为了更有效地向不同的美国群体宣传基因检测，必须考虑文化间差异和语言技能。
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