Liao Yi, Chavez-Yenter Daniel, Kaphingst Kimberly A
Department of Communication, University of Utah, Salt Lake City, Utah, USA.
Division of Hematology-Oncology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Public Health Genomics. 2025;28(1):229-240. doi: 10.1159/000546903. Epub 2025 Jun 18.
This study examined applied knowledge about BRCA testing among Spanish-preferring Latino adults in the USA and identifies factors influencing this knowledge, addressing gaps in understanding genetic literacy within this demographic.
A national survey was conducted with 196 Spanish-preferring Latino adults. Participants completed a questionnaire measuring applied knowledge of BRCA testing, acculturation variables, and literacy measures. Linear regression analysis explored relationships between these factors and applied knowledge scores.
The mean applied knowledge score was 2.33 out of 6, with 26.7% of participants scoring zero. Regression analysis revealed that younger age, female, higher education, higher e-health literacy, and higher numeracy were associated with greater applied knowledge. US identity and critical media literacy were negatively associated with applied knowledge scores.
Spanish-preferring Latino adults demonstrated lower applied knowledge of BRCA testing compared to the general US population, highlighting a significant knowledge disparity. The study identified key factors influencing applied knowledge, such as age, ethnic identity, and e-health literacy, providing insights for developing targeted interventions to improve genetic literacy in this population. These findings can inform culturally competent genetic education initiatives to enhance health outcomes and decision-making regarding genetic testing among Spanish-preferring Latinos.
本研究调查了美国倾向于使用西班牙语的拉丁裔成年人对BRCA检测的应用知识，并确定了影响这些知识的因素，填补了这一人群在基因素养理解方面的空白。
对196名倾向于使用西班牙语的拉丁裔成年人进行了一项全国性调查。参与者完成了一份问卷，该问卷测量了BRCA检测的应用知识、文化适应变量和素养指标。线性回归分析探讨了这些因素与应用知识得分之间的关系。
应用知识的平均得分在6分制中为2.33分，26.7%的参与者得分为零。回归分析显示，年龄较小、女性、高等教育、较高的电子健康素养和较高的算术能力与更多的应用知识相关。美国身份认同和批判性媒体素养与应用知识得分呈负相关。
与美国普通人群相比，倾向于使用西班牙语的拉丁裔成年人对BRCA检测的应用知识较低，凸显了显著的知识差距。该研究确定了影响应用知识的关键因素，如年龄、族裔身份和电子健康素养，为制定有针对性的干预措施以提高这一人群的基因素养提供了见解。这些发现可为具有文化胜任力的基因教育倡议提供参考，以改善健康结果，并促进倾向于使用西班牙语的拉丁裔人群在基因检测方面的决策。
