Skaljac-Staudt G, Ciglar I, Sutalo J, Cvorisćec D
Stomatoloskog Fakulteta u Zagrebu.
Acta Stomatol Croat. 1991;25(1):33-8.
The presence of immunoglobulins G, A and M was studied in human dental pulps using a quantitative method of radial immunodiffusion. Valid data on the amounts of IgG, IgA and IgM were obtained on the basis of measured concentrations of immunoglobulins in each pulp sample and their correlation with total protein concentrations. The results indicated IgG to be present in 100%, IgA in 15% and IgM in 8% of 13 pulp samples affected by chronic inflammation. The mean values of IgG, IgA and IgM thus determined were 84.3, 4.4 and 1.4 mg/g protein, respectively. In intact pulp tissue, however, no presence of immunoglobulins G, A and M could be detected using the same method as above. The results obtained suggested the possibility of local synthesis of immunoglobulins in chronically inflamed pulp tissue, indicated that nonspecific inflammatory reaction may have occurred concurrently with some specific immunologic reactions. The predominance of IgG pointed to immunologic reactions of early types II and III hypersensitivity.
采用放射免疫扩散定量法对人牙髓中的免疫球蛋白G、A和M进行了研究。根据每个牙髓样本中免疫球蛋白的测量浓度及其与总蛋白浓度的相关性，获得了关于IgG、IgA和IgM含量的有效数据。结果表明，在13个受慢性炎症影响的牙髓样本中，100%存在IgG，15%存在IgA，8%存在IgM。由此确定的IgG、IgA和IgM的平均值分别为84.3、4.4和1.4mg/g蛋白质。然而，在完整的牙髓组织中，使用上述相同方法未检测到免疫球蛋白G、A和M的存在。所获得的结果表明，在慢性炎症牙髓组织中可能存在免疫球蛋白的局部合成，表明非特异性炎症反应可能与某些特异性免疫反应同时发生。IgG的优势表明早期II型和III型超敏反应的免疫反应。
