Ciglar I, Sutalo J, Sjaljac-Staudt G, Bozikov J
Stomatoloski Fakultet u Zagrebu.
Acta Stomatol Croat. 1991;25(3):143-9.
Saliva is an important factor upon which general health of the oral cavity is dependent and which influences the occurrence of caries. In diabetic patients, xerostomia may occur due to pronounced polyuria in non-regulated and inadequately regulated cases. The aim of this study was to determine the amount of stimulated saliva and salivary pH in diabetic patients and in normal subjects, and to study the possible difference in the occurrence of caries. Results pointed to a significant decrease in the amount of stimulated saliva in insulin dependent diabetics (1.22 ml/min vs. 1.43 ml/min in normal subjects; p less than 0.01). The lowest amount of stimulated saliva was found in non-regulated diabetics (1.00 ml/min). In all diabetic patients, a significantly lower salivary pH was recorded as compared to normal subjects (p less than 0.01). The DMFS index was significantly higher in both insulin dependent and non-insulin dependent diabetics as compared to normal subjects (p less than 0.01). Concerning the state of diabetes control, significant differences at the level of p less than 0.01 in the DMFS index were observed among all groups of subjects (normal subjects, and regulated, inadequately regulated and non-regulated diabetics). A decreased salivary flow and pH may represent one from a series of caries risk factors in diabetics, especially in inadequately regulated and non-regulated cases of the disease.
唾液是口腔整体健康所依赖的重要因素，并且会影响龋齿的发生。在糖尿病患者中，在未得到控制和控制不佳的情况下，由于明显的多尿可能会发生口干症。本研究的目的是测定糖尿病患者和正常受试者的刺激性唾液量和唾液pH值，并研究龋齿发生率的可能差异。结果表明，胰岛素依赖型糖尿病患者的刺激性唾液量显著减少（1.22毫升/分钟，而正常受试者为1.43毫升/分钟；p<0.01）。未得到控制的糖尿病患者的刺激性唾液量最低（1.00毫升/分钟）。与正常受试者相比，所有糖尿病患者的唾液pH值均显著降低（p<0.01）。与正常受试者相比，胰岛素依赖型和非胰岛素依赖型糖尿病患者的DMFS指数均显著更高（p<0.01）。关于糖尿病的控制状态，在所有受试者组（正常受试者、病情得到控制的糖尿病患者、控制不佳的糖尿病患者和未得到控制的糖尿病患者）之间，DMFS指数在p<0.01水平上存在显著差异。唾液流量和pH值降低可能是糖尿病患者一系列龋齿危险因素之一，尤其是在病情控制不佳和未得到控制的情况下。
