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反射分光光度计:皮肤科医生用于皮肤分型的血压计?

Reflectance spectrophotometer: the dermatologists' sphygmomanometer for skin phototyping?

作者信息

Pershing Lynn K, Tirumala Vidyanath P, Nelson Joel L, Corlett Judy L, Lin Anne G, Meyer Laurence J, Leachman Sancy A

机构信息

Department of Dermatology, University of Utah, Salt Lake City, Utah 84108-1806, USA.

出版信息

J Invest Dermatol. 2008 Jul;128(7):1633-40. doi: 10.1038/sj.jid.5701238. Epub 2008 Jan 17.

Abstract

To date, human skin phototype (SPT) has been determined subjectively by self- or trained investigator assessment using sun burning and/or sun tanning responses, ethnicity, hair, and eye color. This study evaluated objective reflectance spectrophotometer (RS) assessment of SPT in 353 males or females (18-72 years old with Fitzpatrick SPT I-VI) using the area-under-the-intensity curve (AUIC) over the 450-615 nm wavelength interval of reflected light (AUIC). Photoprotected constitutive skin color sites produced higher AUIC values than photo-exposed facultative skin color sites. Constitutive skin color at the upper volar arm was equal to the buttocks. Within-site and between-site AUIC reproducibility of constitutive skin color at the upper volar arm was 3 and 5% coefficient of variation (CV), respectively, which was similar to seasonal variability (8% CV). AUIC values decreased proportionately at both constitutive and facultative sites as a function of increasing SPT from I to VI (r=0.8). RS-measured constitutive skin color at the upper volar arm fit a quadratic equation (r(2)=0.94) that differentiated (P<0.05) between each of the six SPTs and agreed +/-1 SPT category with clinician-assessed SPT. Thus, RS assessment of constitutive skin color at the upper volar arm provides a quick, noninvasive, precise, and accurate method to objectively determine SPT.

摘要

迄今为止,人类皮肤光类型(SPT)一直是通过自我评估或由经过培训的研究人员根据晒伤和/或晒黑反应、种族、头发和眼睛颜色进行主观判定的。本研究使用反射光在450 - 615纳米波长区间的强度曲线下面积(AUIC),对353名男性或女性(年龄在18 - 72岁,Fitzpatrick皮肤光类型为I - VI型)的SPT进行了客观反射分光光度计(RS)评估。光保护的本质性皮肤颜色部位产生的AUIC值高于光暴露的适应性皮肤颜色部位。上臂内侧的本质性皮肤颜色与臀部相等。上臂内侧本质性皮肤颜色的部位内和部位间AUIC可重复性分别为变异系数(CV)3%和5%,这与季节性变化(CV 8%)相似。随着SPT从I型增加到VI型,本质性和适应性部位的AUIC值均成比例下降(r = 0.8)。RS测量的上臂内侧本质性皮肤颜色符合一个二次方程(r² = 0.94),该方程能区分(P < 0.05)六种SPT中的每一种,并且与临床医生评估的SPT相差±1个SPT类别。因此,对上臂内侧本质性皮肤颜色进行RS评估提供了一种快速、无创、精确且准确的方法来客观确定SPT。

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