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慢性鼻窦炎内镜鼻窦手术的长期疗效分析

Long-term outcome analysis of endoscopic sinus surgery for chronic sinusitis.

作者信息

Young Jonathan, Frenkiel Saul, Tewfik Marc A, Mouadeb Debbie A

机构信息

McGill University, Montreal, Quebec, Canada.

出版信息

Am J Rhinol. 2007 Nov-Dec;21(6):743-7. doi: 10.2500/ajr.2007.21.3108.

Abstract

BACKGROUND

The purpose of this study was to determine long-term subjective outcome of endoscopic sinus surgery (ESS) for chronic sinusitis (CS) and to evaluate prognostic indicators for surgical treatment failure.

METHODS

This is a prospective study of patients who underwent ESS for CS. Symptom assessment was performed using a visual analog scale at a pretreatment interview and then at regular intervals post-ESS for up to a 3-year period. The indicators for symptom scoring were nasal obstruction, facial pain, postnasal drip, anterior discharge, and anosmia/hyposmia.

RESULTS

Data analysis indicates that ESS improves symptom scoring early on, but the effects begin to dissipate over time. Anosmia/hyposmia is the most severe symptom overall for all patient subgroups and recurs to a greater degree 3 years postoperatively in Samter's Triad sufferers (p = 0.006), asthmatic patients (p = 0.002), and those with a worse CT scan at presentation (p = 0.04). In addition, Triad sufferers who complain of nasal obstruction and anterior nasal discharge have a significant recurrence of their symptoms postoperatively (p = 0.04 and 0.001, respectively).

CONCLUSION

Individuals must be warned that ESS may not be a long-term solution for CS because of its chronic nature. Patients are relieved of their symptoms initially; however, these tend to recur over a 3-year period. Samter's Triad is the strongest determinant of long-term treatment failure. Asthma also is a determinant of treatment failure, which lends credence to the notion of combined airway disease. Allergy was not a strong determinant of treatment failure in our study.

摘要

背景

本研究的目的是确定慢性鼻窦炎(CS)内镜鼻窦手术(ESS)的长期主观结果,并评估手术治疗失败的预后指标。

方法

这是一项对接受ESS治疗CS患者的前瞻性研究。在治疗前访谈时使用视觉模拟量表进行症状评估,然后在ESS术后定期进行评估,最长为期3年。症状评分指标包括鼻塞、面部疼痛、鼻后滴漏、前鼻漏和嗅觉减退/嗅觉丧失。

结果

数据分析表明,ESS早期可改善症状评分,但随着时间推移效果开始消退。嗅觉减退/嗅觉丧失是所有患者亚组中总体最严重的症状,在Samter三联征患者(p = 0.006)、哮喘患者(p = 0.002)以及就诊时CT扫描结果较差的患者(p = 0.04)中,术后3年复发程度更高。此外,抱怨鼻塞和前鼻漏的三联征患者术后症状有显著复发(分别为p = 0.04和0.001)。

结论

必须告知患者,由于CS的慢性性质,ESS可能不是其长期解决方案。患者最初症状会缓解;然而,这些症状在3年内往往会复发。Samter三联征是长期治疗失败的最强决定因素。哮喘也是治疗失败的一个决定因素,这支持了联合气道疾病的观点。在我们的研究中,过敏不是治疗失败的强决定因素。

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