Merz T, Hazra R, Ross M, Ciborowski L
AJR Am J Roentgenol. 1976 Aug;127(2):337-9. doi: 10.2214/ajr.127.2.337.
Two types of assay systems to measure the effect of radiation on immune competence are described. The first, transformation, is measured by blast formation or uptake and incorporation of tritiated thymidine by lumphocytes. This measure is affected by a number of known cell responses to radiation such as division delay and delay in DNA synthesis. The second, called Bactec, is designed to measure lymphocyte metabolic acitivty. Data gathered on 37 patients with lung cancer show that the Bactec system provides a better index of the patient's immune status before and after radiation therapy.
本文描述了两种用于测量辐射对免疫能力影响的检测系统。第一种是转化检测，通过淋巴细胞的母细胞形成或氚标记胸腺嘧啶核苷的摄取与掺入来进行测量。这一测量受到许多已知的细胞对辐射的反应的影响，如分裂延迟和DNA合成延迟。第二种称为Bactec，旨在测量淋巴细胞代谢活性。对37例肺癌患者收集的数据表明，Bactec系统能更好地反映放疗前后患者的免疫状态。
