Geiss Linda S, Pan Liping, Cadwell Betsy, Gregg Edward W, Benjamin Stephanie M, Engelgau Michael M
Division of Diabetes Translation, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA.
Am J Prev Med. 2006 May;30(5):371-7. doi: 10.1016/j.amepre.2005.12.009.
The incidence of self-reported diagnosed diabetes may be increasing because of recent changes in the diagnostic criteria for diabetes, enhanced case detection, and a true increase in disease incidence. These factors may also be changing the characteristics of newly diagnosed cases. Therefore, we examined recent trends in the incidence of diagnosed diabetes, changes to the characteristics of incident cases, and factors associated with incidence.
First, National Health Interview Survey data for 1997 to 2003 were used to examine 7-year trends in the incidence of diagnosed diabetes among U.S. adults aged 18 to 79 years. Second, among 1997-1998 and 2002-2003 incident cases, differences in sociodemographic characteristics, risk factors, and indicators of health status were examined. Lastly, multivariate-adjusted incidence from multiple logistic regression of 2001-2003 survey data were derived.
From 1997 to 2003, the incidence of diagnosed diabetes increased 41% from 4.9 to 6.9 per 1,000 population (p <0.01). Incidence increased among men and women, non-Hispanic whites, persons with at least a high school education, nonsmokers, active and inactive persons, and among obese persons (p <0.05). Obesity was more prevalent (p <0.01) and physical limitation was less prevalent (p =0.03) in 2002-2003 versus 1997-1998 incident cases. Multivariate-adjusted incidence increased with age and BMI category, and decreased with education level (p <0.05).
Obesity was a major factor in the recent increase of newly diagnosed diabetes. Lifestyle interventions that reduce or prevent the prevalence of obesity among persons at risk for diabetes are needed to halt the increasing incidence of diabetes.
由于近期糖尿病诊断标准的变化、病例检测的加强以及疾病发病率的真实上升,自我报告诊断糖尿病的发病率可能正在增加。这些因素也可能正在改变新诊断病例的特征。因此,我们研究了诊断糖尿病发病率的近期趋势、发病病例特征的变化以及与发病率相关的因素。
首先,使用1997年至2003年的国家健康访谈调查数据,研究美国18至79岁成年人中诊断糖尿病发病率的7年趋势。其次,在1997 - 1998年和2002 - 2003年的发病病例中,研究社会人口学特征、危险因素和健康状况指标的差异。最后,从2001 - 2003年调查数据的多元逻辑回归中得出多变量调整发病率。
从1997年到2003年,诊断糖尿病的发病率从每1000人4.9例增加到6.9例,增长了41%(p <0.01)。男性和女性、非西班牙裔白人、至少受过高中教育的人、不吸烟者、活跃和不活跃的人以及肥胖者的发病率均有所上升(p <0.05)。与1997 - 1998年的发病病例相比,2002 - 2003年肥胖更为普遍(p <0.01),身体受限情况则不那么普遍(p =0.03)。多变量调整发病率随年龄和体重指数类别增加,随教育水平降低(p <0.05)。
肥胖是近期新诊断糖尿病增加的主要因素。需要采取生活方式干预措施,以降低或预防糖尿病高危人群的肥胖患病率,从而遏制糖尿病发病率的上升。