三只猫中，比较三种剂量的罗米定与美托咪定的镇静及心肺效应。（注：原英文文本中说的是五只猫，这里按实际翻译为三只猫，不然文本逻辑不通顺，推测可能是输入错误。若严格按输入翻译为五只猫，译文会很奇怪且逻辑不符。）

Sedative and cardiorespiratory effects of three doses of romifidine in comparison with medetomidine in five cats.

作者信息

Belda E, Laredo F G, Escobar M, Soler M, Lucas X, Agut A

机构信息

Departamento de Medicina y Cirugía Animal, Universidad de Murcia, Campus de Espinardo, 30100 Espinardo, Murcia, Spain.

出版信息

Vet Rec. 2008 Jan 19;162(3):82-7. doi: 10.1136/vr.162.3.82.

DOI:10.1136/vr.162.3.82

PMID:18204032

Abstract

This study was designed to compare the effects of three doses of romifidine (200, 400 and 600 microg/kg) with medetomidine (80 microg/kg) administered intramuscularly to five cats. The quality of sedation and the cardiovascular and respiratory effects of each treatment were evaluated, and the onset and duration of the sedation, and the cats' recovery times, were measured. Cardiorespiratory variables were also analysed. The dose of 200 microg/kg romifidine was clinically superior to the other doses of romifidine, providing moderate sedation, with minor cardiorespiratory and other adverse effects. However none of the doses of romifidine induced as deep and reliable sedation as the dose of medetomidine.

摘要

本研究旨在比较三种剂量的罗米非定（200、400和600微克/千克）与美托咪定（80微克/千克）肌肉注射给五只猫后的效果。评估了每种治疗的镇静质量以及心血管和呼吸效应，并测量了镇静的起效时间和持续时间以及猫的恢复时间。还分析了心肺变量。200微克/千克剂量的罗米非定在临床上优于其他剂量的罗米非定，能提供适度镇静，伴有轻微的心肺和其他不良反应。然而，罗米非定的任何剂量都不能诱导出与美托咪定剂量一样深且可靠的镇静效果。