Liu Lihua, Kumar Satish K S, Sedghizadeh Parish P, Jayakar Abheer N, Shuler Charles F
Los Angeles Cancer Surveillance Program, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Apr;105(4):470-80. doi: 10.1016/j.tripleo.2007.07.007. Epub 2008 Feb 21.
The aim of this report was to examine the oral cancer incidence by sex, race/ethnicity, and anatomical subsite.
Data from the California Cancer Registry (CCR) were used to calculate the age-adjusted incidence rates of invasive oral squamous cell carcinoma (OSCC) by sex, race/ethnicity, and anatomical subsite among residents in California during 1988 to 2001.
Although non-Hispanic (NH) black men have the highest overall incidence rate for OSCC, NH whites and NH blacks have similar incidence patterns by subsite, but the male-to-female (M:F) rate ratio is higher among NH blacks. The OSCC incidence rates for Hispanics are much lower than those for NH whites and NH blacks and similar to those of Asians. The Asian ethnic groups display dramatic variations in terms of the subsite-specific incidence rates and M:F rate ratios.
The findings illustrate the heterogeneity and complexity of oral cancer by anatomical location and the importance of cultural habits and behavioral factors in the development of oral cancer.
本报告旨在按性别、种族/族裔和解剖亚部位研究口腔癌发病率。
利用加利福尼亚癌症登记处（CCR）的数据计算1988年至2001年期间加利福尼亚居民中侵袭性口腔鳞状细胞癌（OSCC）按性别、种族/族裔和解剖亚部位调整年龄后的发病率。
尽管非西班牙裔（NH）黑人男性的OSCC总体发病率最高，但NH白人和NH黑人按亚部位的发病率模式相似，但NH黑人的男女发病率比（M:F）更高。西班牙裔的OSCC发病率远低于NH白人和NH黑人，与亚洲人相似。亚洲族裔在亚部位特异性发病率和男女发病率比方面表现出巨大差异。
研究结果说明了口腔癌按解剖部位的异质性和复杂性，以及文化习惯和行为因素在口腔癌发生中的重要性。
