Ockenfels H M, Hammes S
Haut- und Allergieklinik, Klinikum Stadt Hanau, Leimenstrasse 20, 63450, Hanau.
Hautarzt. 2008 Feb;59(2):116-23. doi: 10.1007/s00105-007-1468-9.
Human papilloma viruses (HPV) lead to common warts in 5% of the population and genital warts in 1% of sexually-active individuals. Although about 50% of HPV infections regress spontaneously, the course is uncertain. Expectant waiting often leads to progression and dissemination. Plantar warts may cause pain on walking, while palmar and genital warts may impair social contacts. There are many treatments for warts, including a variety of laser systems. The CO(2) laser is the best ablative approach, producing cure rates of up to 75% for therapy-resistant common warts in cohort and case-control studies. Side effects such as bleeding, pain and reduced function over weeks must be weighed against the likelihood of success. Considering non-ablative approaches, pulsed dye lasers can be used for a selective, non-bloody destruction of extragenital and genital warts and may become the treatment of choice. In prospective randomized studies, they produced cure rates of up to 82% for therapy-resistant warts with few side effects.
人乳头瘤病毒(HPV)在5%的人群中引发寻常疣,在1%的性活跃个体中引发尖锐湿疣。虽然约50%的HPV感染会自发消退,但病程不确定。等待观察往往会导致病情进展和扩散。跖疣可能导致行走时疼痛,而掌疣和尖锐湿疣可能会影响社交。治疗疣的方法有很多,包括各种激光系统。二氧化碳激光是最佳的消融方法,在队列研究和病例对照研究中,对难治性寻常疣的治愈率高达75%。数周内出现的出血、疼痛和功能减退等副作用必须与成功的可能性相权衡。考虑到非消融方法,脉冲染料激光可用于选择性、无血地破坏生殖器外和生殖器疣,可能会成为首选治疗方法。在前瞻性随机研究中,其对难治性疣的治愈率高达82%,且副作用较少。