Ghonemy Soheir
a Dermatology, Venereology, and Andrology Department, Faculty of Human Medicine , Zagazig University , Zagazig , Egypt.
J Cosmet Laser Ther. 2017 Oct;19(6):347-352. doi: 10.1080/14764172.2017.1326608. Epub 2017 May 10.
Treatment for recalcitrant plantar warts remains a continuing challenge as the options for treatment have differing levels of success. long-pulsed Nd:YAG laser is considered a good treatment modality in resistant plantar warts. On the other hand, high cure rates have been reported with a topical proprietary formulation consisting of 1% cantharidin, 5% podophyllotoxin, 30% salicylic acid.
To compare the efficacy of 1% cantharidin, 20% podophylline resin and 30% salicylic acid (CPS) versus long-pulsed Nd:YAG laser in the treatment of recalcitrant plantar warts.
This study included 30 patients with single or multiple recalcitrant plantar warts; patients were assigned to two groups: the first group included 15 patients with 71 recalcitrant plantar warts who were treated by long-pulsed Nd:YAG laser (group I) and the second group included 15 patients with 78 recalcitrant plantar warts who received CPS (group II). The diagnosis of plantar warts was made by clinical examination.
Fourteen patients (93%) were completely cleared of their warts with topical CPS, while 11 patients (73%) showed complete clearance with long-pulsed Nd:YAG laser with statistically significant difference between the two groups.
Topical CPS is safe and efficacious and represents a promising therapeutic modality than long-pulsed Nd:YAG laser in the treatment of recalcitrant plantar warts.
由于治疗方法的成功率各不相同，顽固性跖疣的治疗仍然是一个持续的挑战。长脉冲钕：钇铝石榴石激光被认为是治疗顽固性跖疣的一种良好治疗方式。另一方面，据报道，一种由1%斑蝥素、5%鬼臼毒素、30%水杨酸组成的外用专利配方具有较高的治愈率。
比较1%斑蝥素、20%鬼臼树脂和30%水杨酸（CPS）与长脉冲钕：钇铝石榴石激光治疗顽固性跖疣的疗效。
本研究纳入30例单发或多发顽固性跖疣患者；患者被分为两组：第一组包括15例患有71个顽固性跖疣的患者，采用长脉冲钕：钇铝石榴石激光治疗（第一组），第二组包括15例患有78个顽固性跖疣的患者，接受CPS治疗（第二组）。跖疣的诊断通过临床检查做出。
14例患者（93%）使用外用CPS后疣体完全清除，而11例患者（73%）使用长脉冲钕：钇铝石榴石激光后疣体完全清除，两组之间存在统计学显著差异。
外用CPS安全有效，在治疗顽固性跖疣方面比长脉冲钕：钇铝石榴石激光更具前景。
