[Evaluation of the effect of mianserin om hemodynamic indicators in patients with endogenous depression].

30 patients (25 males and 5 females) treated clinically with mianserin for a depressive episode in the course of unipolar affective illness was examined for hemodynamic problems using a radiocardiographic method. After two weeks of treatment Total Peripheral Resistance Index (TPRI) and blood pressure diminished significantly compared to basal pretreatment levels. A clear decrease of TPRI during the treatment may be a positive prognostic sign.