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挪威女性大型队列研究中自我报告的黑色素瘤风险因素的可重复性

Reproducibility of self-reported melanoma risk factors in a large cohort study of Norwegian women.

作者信息

Veierød Marit B, Parr Christine L, Lund Eiliv, Hjartåker Anette

机构信息

Institute of Basic Medical Sciences, Department of Biostatistics, University of Oslo, Norway.

出版信息

Melanoma Res. 2008 Feb;18(1):1-9. doi: 10.1097/CMR.0b013e3282f120d2.

Abstract

We studied the test-retest reproducibility of melanoma risk factors, including the use of sunscreen and sun protection factor (SPF), in a self-administered exposure follow-up questionnaire from the Norwegian Women and Cancer Study, a large national population-based cohort. In 2002, a random sample of 2000 women (46-75 years) received the questionnaire twice, about 3 months a part (response 75%). Kappa (kappa) was 0.77 for freckling when sunbathing [95% confidence interval (CI), 0.74-0.81]. Weighted kappa, kappaw, for sunbathing vacations to southern latitudes and solarium use last 5 years was 0.71 (95% CI, 0.68-0.74) and 0.70 (95% CI, 0.67-0.73), respectively. Reproducibility was also good for sunscreen use (yes/no) on specific occasions (0.64< or =kappa< or =0.74) and the corresponding SPF. Spearman's correlation coefficient (r(s)) for SPF on sunbathing vacations to southern latitudes was 0.73 (95% CI, 0.69-0.77) for today and 0.71 (95% CI, 0.66-0.76) for 10 years ago. For the eight most common sunscreen brands, reproducibility was lower for use (yes/no) (0.31< or =kappa< or =0.60) than for SPF (0.38< or =r(s)< or =0.87). The frequency of sunburn and sunbathing vacations in Norway or outside southern latitudes had fair reproducibility (kappaw was 0.49 and 0.47, respectively). Other studies have also found it challenging to measure sunburn. This study was larger than previous studies, permitting subgroup analyses. In conclusion, the overall reproducibility of the questionnaire was acceptable and not affected by age, education or skin color. In particular, our study has added new knowledge about the reproducibility of sunscreen use and SPF.

摘要

我们在挪威女性与癌症研究(一项基于全国大规模人群的队列研究)的自我管理暴露随访问卷中,研究了黑色素瘤风险因素的重测信度,这些因素包括防晒霜的使用和防晒系数(SPF)。2002年,随机抽取的2000名年龄在46至75岁之间的女性接受了两次问卷调查,两次调查间隔约3个月(应答率为75%)。日光浴时雀斑的kappa值为0.77 [95%置信区间(CI),0.74 - 0.81]。过去5年到南半球进行日光浴度假和使用日光浴室的加权kappa值(kappaw)分别为0.71(95% CI,0.68 - 0.74)和0.70(95% CI,0.67 - 0.73)。特定场合下防晒霜使用情况(是/否)及其相应的SPF的重测信度也较好(0.64≤kappa≤0.74)。到南半球进行日光浴度假时,今日SPF的Spearman相关系数(r(s))为0.73(95% CI,0.69 - 0.77),10年前为0.71(95% CI,0.66 - 0.76)。对于八种最常见的防晒霜品牌,使用情况(是/否)的重测信度(0.31≤kappa≤0.60)低于SPF的重测信度(0.38≤r(s)≤0.87)。在挪威或南半球以外地区晒伤和日光浴度假的频率具有中等重测信度(kappaw分别为0.49和0.47)。其他研究也发现测量晒伤具有挑战性。本研究规模大于以往研究,允许进行亚组分析。总之,问卷的总体重测信度是可以接受的,且不受年龄、教育程度或肤色影响。特别是,我们的研究增加了关于防晒霜使用和SPF重测信度的新知识。

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