Batty G David, Deary Ian J, Schoon Ingrid, Emslie Carol, Hunt Kate, Gale Catharine R
UK Medical Research Council Social & Public Health Sciences Unit, University of Glasgow, Glasgow, Scotland, UK.
Am J Public Health. 2008 Dec;98(12):2237-43. doi: 10.2105/AJPH.2007.109488. Epub 2008 Jan 30.
We examined the potential relation of mental ability test scores at age 10 years with alcohol problems and alcohol intake at age 30 years.
We used data from a prospective observational study involving 8170 members of a birth cohort from Great Britain born in 1970. Data included mental ability scores at age 10 years and responses to inquiries about alcohol intake and problems at age 30 years.
After adjustment for potential mediating and confounding factors, cohort members with higher childhood mental ability scores had an increased prevalence of problem drinking in adulthood. This association was stronger among women (odds ratio [OR](1 SD increase in ability) = 1.38; 95% confidence interval [CI] = 1.16, 1.64) than men (OR(1 SD increase in ability) = 1.17; CI = 1.04, 1.28; P for interaction = .004). Childhood mental ability was also related to a higher average intake of alcohol and to drinking more frequently. Again, these gradients were stronger among women than among men.
In this large-scale cohort study, higher childhood mental ability was related to alcohol problems and higher alcohol intake in adult life. These unexpected results warrant examination in other studies.
我们研究了10岁时的心理能力测试分数与30岁时的酒精问题及酒精摄入量之间的潜在关系。
我们使用了一项前瞻性观察性研究的数据,该研究涉及1970年出生于英国的一个出生队列中的8170名成员。数据包括10岁时的心理能力分数以及对30岁时酒精摄入量和问题的询问的回答。
在对潜在的中介和混杂因素进行调整后,童年心理能力分数较高的队列成员在成年期出现饮酒问题的患病率增加。这种关联在女性中(能力每增加1个标准差的优势比[OR]=1.38;95%置信区间[CI]=1.16,1.64)比男性中(能力每增加1个标准差的OR=1.17;CI=1.04,1.28;交互作用P值=.004)更强。童年心理能力还与更高的平均酒精摄入量以及更频繁饮酒有关。同样,这些梯度在女性中比在男性中更强。
在这项大规模队列研究中,较高的童年心理能力与成年生活中的酒精问题和更高的酒精摄入量有关。这些意外结果值得在其他研究中进行检验。