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童年时期的智力与成年后过早死亡的风险因素之间的关系:1970年英国队列研究。

Mental ability across childhood in relation to risk factors for premature mortality in adult life: the 1970 British Cohort Study.

作者信息

Batty G David, Deary Ian J, Schoon Ingrid, Gale Catharine R

机构信息

MRC Social & Public Health Sciences Unit, University of Glasgow, 4 Lilybank Gardens, Glasgow G12 8RZ, UK.

出版信息

J Epidemiol Community Health. 2007 Nov;61(11):997-1003. doi: 10.1136/jech.2006.054494.

Abstract

OBJECTIVE

To examine the relation of scores on tests of mental ability across childhood with established risk factors for premature mortality at the age of 30 years.

METHODS

A prospective cohort study based on members of the British Cohort Study born in Great Britain in 1970 who had complete data on IQ scores at five (N = 8203) or 10 (N = 8171) years of age and risk factors at age 30 years.

RESULTS

In sex-adjusted analyses, higher IQ score at age 10 years was associated with a reduced prevalence of current smoking (OR(per 1 SD advantage in IQ) 0.84; 95% CI 0.80, 0.88), overweight (0.88; 0.84, 0.92), obesity (0.84; 0.79, 0.92), and hypertension (0.90; 0.83, 0.98), and an increased likelihood of having given up smoking by the age of 30 years (1.25; 1.18, 1.24). These gradients were attenuated after adjustment for markers of socioeconomic circumstances across the life course, particularly education. There was no apparent relationship between IQ and diabetes. Essentially the same pattern of association was evident when the predictive value of IQ scores at five years of age was examined.

CONCLUSIONS

The mental ability-risk factor gradients reported in the present study may offer some insights into the apparent link between low pre-adult mental ability and premature mortality.

摘要

目的

研究儿童期心理能力测试得分与30岁时过早死亡的既定风险因素之间的关系。

方法

一项前瞻性队列研究,基于1970年出生在英国的英国队列研究成员,他们拥有5岁(N = 8203)或10岁(N = 8171)时的智商得分完整数据以及30岁时的风险因素数据。

结果

在性别调整分析中,10岁时较高的智商得分与当前吸烟率降低(智商每高出1个标准差的优势比(OR)为0.84;95%置信区间为0.80,0.88)、超重(0.88;0.84,0.92)、肥胖(0.84;0.79,0.92)和高血压(0.90;0.83,0.98)相关,并且到30岁时戒烟的可能性增加(1.25;1.18,1.24)。在对整个生命历程中的社会经济状况指标,特别是教育进行调整后,这些梯度减弱。智商与糖尿病之间没有明显关系。在研究5岁时智商得分的预测价值时,基本相同的关联模式很明显。

结论

本研究报告的心理能力 - 风险因素梯度可能为成年前心理能力低下与过早死亡之间的明显联系提供一些见解。

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