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使用灭活肿瘤细胞疫苗对猫肿瘤病毒病进行免疫接种。

Immunization against feline oncarnavirus disease using a killed tumor cell vaccine.

作者信息

Olsen R G, Hoover E A, Mathes L E, Heding L, Schaller J P

出版信息

Cancer Res. 1976 Oct;36(10):3642-6.

PMID:182360
Abstract

Specific pathogen-free cats were immunized with an inactivated feline oncornavirus tumor cell vaccine. Immunized cats produced high antibody titers to the feline oncornavirus-associated cell membrane antigen and were protected from oncogenic feline sarcoma virus challenge. However, immunization did not produce virus-neutralizing antibody nor did it prevent viremia.

摘要

将无特定病原体的猫用灭活的猫肿瘤病毒疫苗进行免疫。免疫后的猫产生了针对猫肿瘤病毒相关细胞膜抗原的高抗体滴度,并受到保护,免受致癌性猫肉瘤病毒的攻击。然而,免疫并未产生病毒中和抗体,也未能预防病毒血症。

相似文献

1
Immunization against feline oncarnavirus disease using a killed tumor cell vaccine.使用灭活肿瘤细胞疫苗对猫肿瘤病毒病进行免疫接种。
Cancer Res. 1976 Oct;36(10):3642-6.
2
Abrogation of resistance to feline oncornavirus disease by immunization with killed feline leukemia virus.
Cancer Res. 1977 Jul;37(7 Pt 1):2082-5.
3
Protection of cats against progressive fibrosarcomas and persistent leukemia virus infection by vaccination with feline leukemia cells.通过用猫白血病细胞接种疫苗保护猫免受进行性纤维肉瘤和持续性白血病病毒感染。
J Natl Cancer Inst. 1980 Dec;65(6):1285-92.
4
Experimental oncornavirus vaccines in the cat.猫用实验性肿瘤病毒疫苗
Cancer Res. 1976 Feb;36(2 pt 2):646-51.
5
Immune response to leukemia virus and tumor-associated antigens in cats.猫对白血病病毒和肿瘤相关抗原的免疫反应。
Cancer Res. 1976 Feb;36(2 pt 2):640-5.
6
Serum antibodies against feline oncornavirus-associated cell membrane antigen in cats bearing virally induced uveal melanomas.患有病毒诱导性葡萄膜黑色素瘤的猫体内针对猫肿瘤病毒相关细胞膜抗原的血清抗体。
Invest Ophthalmol Vis Sci. 1981 May;20(5):598-605.
7
Protection against feline leukemia virus infection by use of an inactivated virus vaccine.使用灭活病毒疫苗预防猫白血病病毒感染。
J Am Vet Med Assoc. 1991 Nov 15;199(10):1392-401.
8
Detection and evaluation of feline oncornavirus-induced cell surface antigen(s) shed from cells in vitro.
Cancer Res. 1977 Nov;37(11):4134-7.
9
[Feline leukemogenic and sarcomatogenic viruses].[猫白血病病毒和肉瘤病毒]
C R Seances Soc Biol Fil. 1975;169(3 Suppl):794-806.
10
Immunosuppressive properties of a virion polypeptide, a 15,000-dalton protein, from feline leukemia virus.来自猫白血病病毒的一种病毒粒子多肽(一种15000道尔顿的蛋白质)的免疫抑制特性。
Cancer Res. 1979 Mar;39(3):950-5.

引用本文的文献

1
Biology of Bordetella bronchiseptica.支气管败血波氏杆菌生物学
Microbiol Rev. 1980 Dec;44(4):722-38. doi: 10.1128/mr.44.4.722-738.1980.
2
Protection against feline leukemia by vaccination with a subunit vaccine.用亚单位疫苗接种预防猫白血病
Infect Immun. 1981 Dec;34(3):888-94. doi: 10.1128/iai.34.3.888-894.1981.
3
Possible immunoenhancement of persistent viremia by feline leukemia virus envelope glycoprotein vaccines in challenge-exposure situations where whole inactivated virus vaccines were protective.在全灭活病毒疫苗具有保护作用的攻毒暴露情况下,猫白血病病毒包膜糖蛋白疫苗可能会增强持续性病毒血症的免疫反应。
Vet Immunol Immunopathol. 1986 Feb;11(2):123-48. doi: 10.1016/0165-2427(86)90093-0.
4
Feline leukemia/sarcoma viruses and immunodeficiency.猫白血病/肉瘤病毒与免疫缺陷
Adv Vet Sci Comp Med. 1988;32:57-96. doi: 10.1016/b978-0-12-039232-2.50007-4.
5
Feline leukemia virus: current status of the feline induced immune depression and immunoprevention.猫白血病病毒:猫诱导性免疫抑制及免疫预防的现状
Cancer Metastasis Rev. 1987;6(3):243-60. doi: 10.1007/BF00144266.
6
Pseudotypes of feline sarcoma virus contain an 85,000-dalton protein with feline oncornavirus-associated cell membrane antigen (FOCMA) activity.猫肉瘤病毒假型包含一种具有猫肿瘤病毒相关细胞膜抗原(FOCMA)活性的85,000道尔顿蛋白质。
Proc Natl Acad Sci U S A. 1978 Mar;75(3):1505-9. doi: 10.1073/pnas.75.3.1505.
7
Passive immunity to feline leukemia: evaluation of immunity from dams naturally infected and experimentally vaccinated.猫白血病的被动免疫:对自然感染和经实验接种疫苗的母猫的免疫评估
Infect Immun. 1977 Apr;16(1):54-9. doi: 10.1128/iai.16.1.54-59.1977.