使用灭活肿瘤细胞疫苗对猫肿瘤病毒病进行免疫接种。
Immunization against feline oncarnavirus disease using a killed tumor cell vaccine.
作者信息
Olsen R G, Hoover E A, Mathes L E, Heding L, Schaller J P
出版信息
Cancer Res. 1976 Oct;36(10):3642-6.
PMID:182360
Abstract
Specific pathogen-free cats were immunized with an inactivated feline oncornavirus tumor cell vaccine. Immunized cats produced high antibody titers to the feline oncornavirus-associated cell membrane antigen and were protected from oncogenic feline sarcoma virus challenge. However, immunization did not produce virus-neutralizing antibody nor did it prevent viremia.
摘要
将无特定病原体的猫用灭活的猫肿瘤病毒疫苗进行免疫。免疫后的猫产生了针对猫肿瘤病毒相关细胞膜抗原的高抗体滴度，并受到保护，免受致癌性猫肉瘤病毒的攻击。然而，免疫并未产生病毒中和抗体，也未能预防病毒血症。
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