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蚊子和蜱虫的解剖学本体论及其在VectorBase中的网络浏览器。

Anatomical ontologies of mosquitoes and ticks, and their web browsers in VectorBase.

作者信息

Topalis P, Tzavlaki C, Vestaki K, Dialynas E, Sonenshine D E, Butler R, Bruggner R V, Stinson E O, Collins F H, Louis C

机构信息

Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Heraklion, Crete, Greece.

出版信息

Insect Mol Biol. 2008 Feb;17(1):87-9. doi: 10.1111/j.1365-2583.2008.00781.x.

Abstract

VectorBase, an integrated, relational database that manages genomic and other genetic/biological data pertaining to arthropod vectors of disease, has recently embarked on the construction of ontologies and controlled vocabularies (CVs). It aims, thus, at providing all necessary tools for the complete annotation of vector genomes and, in particular, the annotation of functional genomic data. This task was initiated with the development of anatomical ontologies of mosquitoes and ticks, both of which were made compliant to CARO, the common anatomy reference ontology. The ontologies are complemented by the development of novel web-based browsers that can show figures for anatomical terms, something that is especially helpful for fully illustrating the controlled vocabularies of anatomy.

摘要

VectorBase是一个集成的关系数据库,用于管理与疾病节肢动物传播媒介相关的基因组及其他遗传/生物学数据,该数据库最近着手构建本体和受控词汇表(CVs)。因此,其目标是提供所有必要工具以对媒介基因组进行完整注释,特别是对功能基因组数据进行注释。这项任务始于蚊子和蜱的解剖学本体的开发,这两种本体均符合通用解剖学参考本体CARO。这些本体通过开发新型基于网络的浏览器得到补充,该浏览器可以显示解剖学术语的图形,这对于充分阐释解剖学的受控词汇表特别有帮助。

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