European Bioinformatics Institute EMBL, Wellcome Trust Genome Campus, Hinxton CB10 1SD, UK.
Nucleic Acids Res. 2012 Jan;40(Database issue):D729-34. doi: 10.1093/nar/gkr1089. Epub 2011 Dec 1.
VectorBase (http://www.vectorbase.org) is a NIAID-supported bioinformatics resource for invertebrate vectors of human pathogens. It hosts data for nine genomes: mosquitoes (three Anopheles gambiae genomes, Aedes aegypti and Culex quinquefasciatus), tick (Ixodes scapularis), body louse (Pediculus humanus), kissing bug (Rhodnius prolixus) and tsetse fly (Glossina morsitans). Hosted data range from genomic features and expression data to population genetics and ontologies. We describe improvements and integration of new data that expand our taxonomic coverage. Releases are bi-monthly and include the delivery of preliminary data for emerging genomes. Frequent updates of the genome browser provide VectorBase users with increasing options for visualizing their own high-throughput data. One major development is a new population biology resource for storing genomic variations, insecticide resistance data and their associated metadata. It takes advantage of improved ontologies and controlled vocabularies. Combined, these new features ensure timely release of multiple types of data in the public domain while helping overcome the bottlenecks of bioinformatics and annotation by engaging with our user community.
VectorBase（http://www.vectorbase.org）是一个由 NIAID 支持的医学昆虫生物信息学资源，用于研究人类病原体的无脊椎动物载体。它提供了九个基因组的数据：蚊子（三种冈比亚按蚊基因组、埃及伊蚊和致倦库蚊）、蜱（Ixodes scapularis）、体虱（Pediculus humanus）、接吻虫（Rhodnius prolixus）和采采蝇（Glossina morsitans）。宿主数据范围从基因组特征和表达数据到群体遗传学和本体论。我们描述了改进和整合新数据，以扩大我们的分类覆盖范围。发布是每两个月一次，包括新兴基因组的初步数据交付。基因组浏览器的频繁更新为 VectorBase 用户提供了越来越多的可视化自己高通量数据的选项。一个主要的发展是一个新的种群生物学资源，用于存储基因组变异、杀虫剂抗性数据及其相关元数据。它利用了改进的本体论和受控词汇。这些新功能结合在一起，确保了多种类型的数据在公共领域的及时发布，同时通过与我们的用户社区合作，帮助克服生物信息学和注释的瓶颈。
