Giraldo-Calderón Gloria I, Emrich Scott J, MacCallum Robert M, Maslen Gareth, Dialynas Emmanuel, Topalis Pantelis, Ho Nicholas, Gesing Sandra, Madey Gregory, Collins Frank H, Lawson Daniel
Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA.
Department of Computer Science and Engineering, University of Notre Dame, Notre Dame, IN 46556, USA ECK Institute for Global Health, University of Notre Dame, Notre Dame, IN 46556, USA
Nucleic Acids Res. 2015 Jan;43(Database issue):D707-13. doi: 10.1093/nar/gku1117. Epub 2014 Dec 15.
VectorBase is a National Institute of Allergy and Infectious Diseases supported Bioinformatics Resource Center (BRC) for invertebrate vectors of human pathogens. Now in its 11th year, VectorBase currently hosts the genomes of 35 organisms including a number of non-vectors for comparative analysis. Hosted data range from genome assemblies with annotated gene features, transcript and protein expression data to population genetics including variation and insecticide-resistance phenotypes. Here we describe improvements to our resource and the set of tools available for interrogating and accessing BRC data including the integration of Web Apollo to facilitate community annotation and providing Galaxy to support user-based workflows. VectorBase also actively supports our community through hands-on workshops and online tutorials. All information and data are freely available from our website at https://www.vectorbase.org/.
VectorBase是一个由美国国立过敏与传染病研究所支持的生物信息学资源中心（BRC），专注于人类病原体的无脊椎传播媒介。如今，VectorBase已成立11年，目前托管着35种生物的基因组，其中包括一些用于比较分析的非传播媒介生物。托管的数据范围广泛，从带有注释基因特征的基因组组装、转录本和蛋白质表达数据，到群体遗传学数据，包括变异和抗杀虫剂表型。在此，我们描述了我们资源的改进情况以及可用于查询和访问BRC数据的一系列工具，包括集成Web Apollo以促进社区注释以及提供Galaxy以支持基于用户的工作流程。VectorBase还通过实践工作坊和在线教程积极支持我们的社区。所有信息和数据均可从我们的网站https://www.vectorbase.org/免费获取。
