摩洛哥南大西洋沿岸贻贝（Perna perna）的麻痹性贝类中毒毒素谱

Paralytic shellfish poisoning toxin profile of mussels Perna perna from southern Atlantic coasts of Morocco.

作者信息

Abouabdellah Rachid, Taleb Hamid, Bennouna Asmae, Erler Katrin, Chafik Abdeghani, Moukrim Abdelatif

机构信息

Institut National de Recherche Halieutique, B.P 5221 Q.I, Agadir, Morroco.

出版信息

Toxicon. 2008 Apr;51(5):780-6. doi: 10.1016/j.toxicon.2007.12.004. Epub 2007 Dec 14.

DOI:10.1016/j.toxicon.2007.12.004

PMID:18237757

Abstract

During the monitoring programme of harmful algal blooms established along the south Atlantic coast of Morocco, a bimonthly determination of harmful algae and phycotoxins analysis in Perna perna was carried out from May 2003 to December 2004. Results of mouse bioassay (in organs and whole flesh) showed a seasonal evolution of paralytic shellfish poisoning (PSP) toxin. The mussel's contamination was associated with the occurrence in water of Alexandrium minutum. The PSP toxin profile obtained with high-performance liquid chromatography (HPLC/FD) revealed the dominance of gonyautoxins GTX2 and GTX3 and a minority of GTX1, GTX4 and saxitoxin (STX). This profile explains that the toxicity was mainly associated with A. minutum.

摘要

在摩洛哥南大西洋沿岸开展的有害藻华监测项目中，于2003年5月至2004年12月对翡翠贻贝中的有害藻类进行了双月测定，并分析了其中的藻毒素。小鼠生物测定（器官和整个肌肉）结果显示麻痹性贝类毒素（PSP）存在季节性变化。贻贝的污染与微小亚历山大藻在水中的出现有关。通过高效液相色谱法（HPLC/FD）获得的PSP毒素谱显示，膝沟藻毒素GTX2和GTX3占主导地位，而GTX1、GTX4和石房蛤毒素（STX）含量较少。这种毒素谱解释了毒性主要与微小亚历山大藻有关。