Kittler Phyllis M, Krinsky-McHale Sharon J, Devenny Darlynne A
Department of Psychology, New York State Institute for Basic Research in Developmental Disabilities, NY 10313, USA.
Am J Ment Retard. 2008 Mar;113(2):117-32. doi: 10.1352/0895-8017(2008)113[117:DPAAMO]2.0.CO;2.
Behavioral phenotypes of individuals with Williams syndrome and individuals with Down syndrome have been contrasted in relation to short-term memory. People with Down syndrome are stronger visuospatially and those with Williams syndrome are stronger verbally. We examined short-term memory, then explored whether dual-task processing further characterized behavioral phenotypes in 53 older adults with Down syndrome, 10 with Williams syndrome, and 39 controls. Short-term memory profiles generally conformed to those of younger individuals. Pegs placement and number repetition were performed singly and simultaneously. There were no etiology group performance differences on single tasks. During concurrent processing, all groups maintained single-task performance on pegs, but declined on number repetition. However, participants with Down syndrome declined more, suggesting relatively greater weakness in the dual-task processing component of executive function for this group.
威廉姆斯综合征患者和唐氏综合征患者的行为表型在短期记忆方面进行了对比。唐氏综合征患者在视觉空间方面更强,而威廉姆斯综合征患者在语言方面更强。我们对短期记忆进行了检查,然后探究双任务处理是否能进一步刻画53名老年唐氏综合征患者、10名威廉姆斯综合征患者和39名对照者的行为表型。短期记忆概况总体上与年轻个体相符。分别单独和同时进行了钉板放置和数字重复任务。在单任务上,病因组之间没有表现差异。在同时进行处理时,所有组在钉板任务上都保持了单任务表现,但在数字重复任务上表现下降。然而,唐氏综合征患者下降得更多,表明该组在执行功能的双任务处理部分相对更弱。