Bateman Grant A
Department of Medical Imaging, John Hunter Hospital, Newcastle Region, Mail Center, Newcastle, New South Wales 2310, Australia.
J Clin Neurosci. 2008 Apr;15(4):402-8. doi: 10.1016/j.jocn.2007.03.018. Epub 2008 Jan 31.
A reduction in the proportion of the arterial inflow drained by the superior sagittal sinus in idiopathic intracranial hypertension (IIH) patients without stenoses has been noted and this has suggested elevated collateral flow. This study defines the interaction between arterial inflow and venous outflow in patients with outflow stenoses and IIH. Forty patients with clinical IIH underwent standard MRI, MR venography and MR flow quantification studies of the cerebral arteries and veins. There were 21/40 patients with venous stenoses. The arterial inflow was 21% higher than normal (p=0.01); however, the superior sagittal sinus outflow was normal, giving a reduced percentage of venous outflow compared to inflow. Seven patients were followed up after remission of their symptoms and the arterial inflows and percentage outflow returned to normal. There is a spectrum of findings in IIH; patients with stenoses have lower inflows than those with patent sinuses but still have evidence of collateral flow.
在无狭窄的特发性颅内高压（IIH）患者中，已注意到由上矢状窦引流的动脉流入比例降低，这提示侧支血流增加。本研究确定了存在流出道狭窄的IIH患者动脉流入与静脉流出之间的相互作用。40例临床诊断为IIH的患者接受了标准的MRI、磁共振静脉血管造影以及脑动脉和静脉的磁共振血流定量研究。40例患者中有21例存在静脉狭窄。动脉流入比正常高21%（p = 0.01）；然而，上矢状窦流出正常，与流入相比，静脉流出百分比降低。7例患者症状缓解后接受随访，动脉流入和流出百分比恢复正常。IIH存在一系列表现；有狭窄的患者流入量低于窦通畅的患者，但仍有侧支血流的证据。
