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骨肉瘤伴跳跃性、淋巴结、肺、胸膜转移及恶性胸腔积液:骨扫描的不寻常表现

Osteogenic Sarcoma Presenting with Skip, Lymph Nodal, Pulmonary, Pleural Metastases and Malignant Effusion: An Unusual Appearance on Bone Scan.

作者信息

Bollampally Neeraja, Krishnaraju Venkata Subramanian, Sood Ashwani, Aggarwal Sameer, Mittal Bhagwant Rai

机构信息

Department of Nuclear Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Department of Orthopeadics, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Indian J Nucl Med. 2021 Jan-Mar;36(1):78-79. doi: 10.4103/ijnm.IJNM_177_20. Epub 2021 Mar 4.

DOI:10.4103/ijnm.IJNM_177_20
PMID:34040306
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8130688/
Abstract

Osteogenic sarcoma is an aggressive malignant bone tumor arising from primitive mesenchymal bone-forming cells. Ossification is the characteristic feature of the metastases in osteosarcoma which aids their detection on Tc-MDP bone scintigraphy. Although lung is the most common site of metastasis in osteogenic sarcoma, pleural involvement with effusion and skip metastases are rare. Herein, we report a case of osteogenic sarcoma of distal femur with diffuse calcified pleural thickening leading to malignant pleural effusion, calcified lung, lymph node, and bone metastases illustrated on bone scan.

摘要

骨肉瘤是一种起源于原始间充质骨形成细胞的侵袭性恶性骨肿瘤。骨化是骨肉瘤转移灶的特征性表现,有助于在锝-亚甲基二膦酸盐(Tc-MDP)骨闪烁显像上检测到它们。虽然肺是骨肉瘤最常见的转移部位,但伴有胸腔积液的胸膜受累及跳跃转移很少见。在此,我们报告一例股骨远端骨肉瘤病例,其表现为弥漫性钙化性胸膜增厚导致恶性胸腔积液,骨扫描显示有钙化的肺部、淋巴结及骨转移。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22b9/8130688/d73166a9f957/IJNM-36-78-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22b9/8130688/ac2eac0cdc1f/IJNM-36-78-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22b9/8130688/d73166a9f957/IJNM-36-78-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22b9/8130688/ac2eac0cdc1f/IJNM-36-78-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22b9/8130688/d73166a9f957/IJNM-36-78-g002.jpg

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本文引用的文献

1
Osteosarcoma presenting with malignant pleural effusion in a 55 year old.一名55岁患者的骨肉瘤伴恶性胸腔积液
Respir Med Case Rep. 2018 Oct 24;25:314-317. doi: 10.1016/j.rmcr.2018.10.017. eCollection 2018.
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Pleural Metastasis of Osteosarcoma.骨肉瘤的胸膜转移
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Review of Osteosarcoma and Current Management.骨肉瘤综述与当前治疗方法
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