Cho Sunghun, Breedlove Jennifer J, Gunning Sean T
Carl R. Darnall Army Medical Center, Department of Dermatology, Fort Hood, TX, USA.
J Drugs Dermatol. 2008 Jan;7(1):64-7.
We present a case of a 55-year-old female with breast cancer who developed radiation recall dermatitis (RRD) 3 years later after administration of levofloxacin. A vast majority of cases occur after administration of chemotherapeutic medications; however, a review of literature implicates increasing numbers of nonchemotherapeutic agents and supplements in RRD. Although the pathophysiology of RRD has yet to be elucidated, the implication of more nonchemotherapeutic agents may favor a drug hypersensitivity etiology. To our knowledge, this is the first report of RRD secondary to levofloxacin.
我们报告一例55岁患乳腺癌的女性，在使用左氧氟沙星3年后发生了放射性回忆性皮炎（RRD）。绝大多数病例发生在使用化疗药物之后；然而，文献综述表明，越来越多的非化疗药物和补充剂也与RRD有关。尽管RRD的病理生理学尚未阐明，但更多非化疗药物的牵涉可能支持药物超敏反应病因。据我们所知，这是首例继发于左氧氟沙星的RRD报告。
