Burke Christopher K, Peirce Jessica M, Kidorf Michael S, Neubauer David, Punjabi Naresh M, Stoller Kenneth B, Hursh Steve, Brooner Robert K
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.
J Subst Abuse Treat. 2008 Oct;35(3):328-33. doi: 10.1016/j.jsat.2007.10.003. Epub 2008 Jan 14.
Treatment-seeking opioid-dependent individuals frequently report sleep-related problems. This study provides a detailed assessment of sleep duration and quality in this population, including their effect on daily functioning and relationship to psychiatric severity and drug use. Samples of newly admitted patients to opioid agonist maintenance treatment (n = 113) completed a series of questionnaires to assess sleep functioning, psychiatric severity, and drug use due to sleep problems over the past 30 days. The results showed that study participants reported considerable sleep-related difficulties that had little effect on their appraisals of daily functioning. Nevertheless, sleep problems were associated with psychiatric distress, and those reporting substance use specifically to increase or decrease sleepiness endorsed more sleep problems and lower levels of daily functioning. Overall, these results replicate and extend previous work showing poor sleep functioning in this population and show that sleep problems are associated with variables that often have an adverse impact on substance abuse treatment outcome.
寻求治疗的阿片类药物依赖个体经常报告与睡眠相关的问题。本研究对该人群的睡眠时间和质量进行了详细评估，包括其对日常功能的影响以及与精神疾病严重程度和药物使用的关系。新入院接受阿片类激动剂维持治疗的患者样本（n = 113）完成了一系列问卷，以评估过去30天内的睡眠功能、精神疾病严重程度以及因睡眠问题导致的药物使用情况。结果表明，研究参与者报告了相当多的与睡眠相关的困难，但这些困难对他们对日常功能的评价影响不大。然而，睡眠问题与精神痛苦有关，那些报告为增加或减少嗜睡而专门使用物质的人认可更多的睡眠问题和更低的日常功能水平。总体而言，这些结果重复并扩展了先前的研究工作，表明该人群睡眠功能较差，并表明睡眠问题与经常对药物滥用治疗结果产生不利影响的变量相关。
