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睡眠与物质使用障碍治疗:强化门诊治疗期间睡眠的主观和客观评估的初步研究。

Sleep and substance use disorder treatment: A preliminary study of subjective and objective assessment of sleep during an intensive outpatient program.

机构信息

Department of Psychiatry and Behavioral Sciences, The Medical University of South Carolina (MUSC), Charleston, South Carolina, USA.

Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA.

出版信息

Am J Addict. 2021 Sep;30(5):477-484. doi: 10.1111/ajad.13194. Epub 2021 Jun 23.

Abstract

BACKGROUND AND OBJECTIVES

Characteristics of sleep concerns and their relationship to mental health in heterogeneous substance use disorder (SUD) treatment settings are not well understood. The purpose of this preliminary study was to assess sleep using subjective and objective measures at two time points during SUD treatment and compare sleep changes to changes in mental health measures.

METHODS

Treatment-seeking participants completed an assessment battery at the beginning of treatment (Time 1, N = 30) and again upon treatment completion (Time 2, approximately 4 weeks later, N = 22). The majority of participants were White (80%), male (63%), and presenting for alcohol use disorder (60.0%), though almost half reported polysubstance abuse (43%). Comorbidity was common (53%). Sleep and mental health questionnaires with 1 week of actigraphy and sleep diaries were completed at both time points.

RESULTS

Most participants met the criteria for a sleep disorder and mean scores on questionnaires showed poor sleep quality, insomnia symptoms, and frequent nightmares, with sleep quality and insomnia improving over time but remaining clinically significant. Nightmares did not improve. Actigraphy indicated poor sleep at both time points. Improvement in insomnia was related to improvement in measures of mental health while changes in actigraphy variables were not related to these measures.

DISCUSSION AND CONCLUSIONS

Multiple types of sleep disturbance are prevalent in this population, with nightmares persisting throughout treatment and insomnia symptoms showing a relationship with mental health symptoms.

SCIENTIFIC SIGNIFICANCE

This was the first study to longitudinally assess mental health with subjective and objective measures of sleep across multiple types of SUDs in a community SUD treatment setting.

摘要

背景与目的

在不同物质使用障碍(SUD)治疗环境中,睡眠问题的特征及其与心理健康的关系尚不清楚。本初步研究的目的是在 SUD 治疗期间的两个时间点使用主观和客观测量来评估睡眠,并将睡眠变化与心理健康测量的变化进行比较。

方法

寻求治疗的参与者在治疗开始时(时间 1,N=30)和治疗完成时(时间 2,大约 4 周后,N=22)完成了评估测试包。大多数参与者为白人(80%),男性(63%),且为酒精使用障碍(60.0%)就诊,尽管近一半报告了多物质滥用(43%)。合并症很常见(53%)。在两个时间点都完成了睡眠和心理健康问卷以及一周的活动记录仪和睡眠日记。

结果

大多数参与者符合睡眠障碍标准,问卷的平均得分表明睡眠质量差、失眠症状和频繁做噩梦,且随着时间的推移睡眠质量和失眠症有所改善,但仍具有临床意义。噩梦并未改善。活动记录仪显示两个时间点的睡眠质量都较差。失眠症的改善与心理健康测量指标的改善有关,而活动记录仪变量的变化与这些测量指标无关。

讨论与结论

该人群中存在多种类型的睡眠障碍,噩梦在整个治疗过程中持续存在,失眠症状与心理健康症状有关。

科学意义

这是第一项在社区 SUD 治疗环境中,针对多种 SUD 使用主观和客观睡眠测量方法进行的纵向评估心理健康的研究。

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