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早产儿的神经影像学与神经发育结局

Neuroimaging and neurodevelopmental outcomes in preterm infants.

作者信息

Hintz Susan R, O'Shea Michael

机构信息

Division of Neonatal and Developmental Medicine, Stanford University School of Medicine, Palo Alto, CA 94304, USA.

出版信息

Semin Perinatol. 2008 Feb;32(1):11-9. doi: 10.1053/j.semperi.2007.12.010.

DOI:10.1053/j.semperi.2007.12.010
PMID:18249235
Abstract

Imaging of the preterm infant brain has advanced dramatically beyond the earliest era of transillumination. Computed tomography (CT), a crucial innovation during the early 1970s, allowed noninvasive visualization of intracerebral lesions, particularly hemorrhage. The capability to document brain injury in the preterm infant led to better clarification of links to developmental outcomes. With the development of cranial ultrasound (CUS), and more recently, magnetic resonance imaging (MRI), CT is used rarely for imaging the brain of preterm infants. Despite extensive experience with neonatal neuroimaging, significant questions still remain. Substantial controversies exist pertaining to when and how neuroimaging should be performed and how images should be interpreted.

摘要

早产儿脑部成像技术已经从最早的透照法时代取得了巨大进步。计算机断层扫描(CT)是20世纪70年代初的一项关键创新技术,它能够对脑内病变,尤其是出血进行无创可视化检查。记录早产儿脑损伤的能力有助于更好地阐明其与发育结局之间的联系。随着头颅超声(CUS)的发展,以及最近磁共振成像(MRI)的出现,CT在早产儿脑部成像中的应用已很少见。尽管在新生儿神经成像方面有丰富经验,但重大问题仍然存在。在何时以及如何进行神经成像以及如何解读图像方面存在大量争议。

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