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每日一餐的时间会影响人体尿中环磷酸腺苷（cAMP）、血液中胰高血糖素、胰岛素和铁的昼夜节律之间的关系。

Timing of single daily meal influences relations among human circadian rhythms in urinary cyclic AMP and hemic glucagon, insulin and iron.

作者信息

Goetz F, Bishop J, Halberg F, Sothern R B, Brunning R, Senske B, Greenberg B, Minors D, Stoney P, Smith I D, Rosen G D, Cressey D, Haus E, Apfelbaum M

出版信息

Experientia. 1976 Aug 15;32(8):1081-4. doi: 10.1007/BF01933983.

DOI:10.1007/BF01933983
PMID:182528
Abstract

Relations among circadian rhythms in serum iron, glucagon and insulin and urinary cyclic AMP excretion differ drastically when diurnally active, nocturnally resting human adults consume all daily food for one week as breakfast only and for another week as dinner only - a finding of interest to diverse fields, e.g., for optimizing certain kinds of therapy or for a better utilization of calories.

摘要

当日间活动、夜间休息的成年人类连续一周仅将一日三餐作为早餐食用，而在接下来的一周仅作为晚餐食用时，血清铁、胰高血糖素和胰岛素的昼夜节律与尿中环磷酸腺苷排泄之间的关系会发生巨大变化——这一发现引起了多个领域的兴趣，例如用于优化某些治疗方法或更好地利用卡路里。

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1
Timing of single daily meal influences relations among human circadian rhythms in urinary cyclic AMP and hemic glucagon, insulin and iron.每日一餐的时间会影响人体尿中环磷酸腺苷（cAMP）、血液中胰高血糖素、胰岛素和铁的昼夜节律之间的关系。
Experientia. 1976 Aug 15;32(8):1081-4. doi: 10.1007/BF01933983.
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J Nutr. 1980 May;110(5):876-82. doi: 10.1093/jn/110.5.876.
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J Nutr. 1977 May;107(5):746-57. doi: 10.1093/jn/107.5.746.
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Circadian rhythms in the urinary excretion of cyclic 3',5'-adenosine monophosphate (cyclic AMP) and cyclic 3',5'-guanosine monophosphate (cyclic GMP) in human subjects.
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Consuming more of daily caloric intake at dinner predisposes to obesity. A 6-year population-based prospective cohort study.

本文引用的文献

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CIRCADIAN RHYTHMIC PITUITARY ADRENOCORTICOTROPIC ACTIVITY, RECTAL TEMPERATURE AND PINNAL MITOSIS OF STARVING, DEHYDRATED C MICE.饥饿、脱水的C小鼠的昼夜节律性垂体促肾上腺皮质激素活性、直肠温度和耳廓有丝分裂
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DETERMINATION OF SERUM IRON USING SULFONATED DIPHENYLPHENANTHROLINE.使用磺化二苯基菲啰啉测定血清铁
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A SIMPLE IMMUNOASSAY FOR INSULIN: APPLICATION TO HUMAN AND DOG PLASMA.一种简单的胰岛素免疫测定法：在人和犬血浆中的应用。
晚餐摄入更多的每日热量会增加肥胖风险。一项基于人群的6年前瞻性队列研究。
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Timing Nutriceuticals?适时的营养保健品？
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Circadian changes of drug disposition in man.人体药物处置的昼夜变化。
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Does 'anchor sleep' entrain circadian rhythms? Evidence from constant routine studies.“锚定睡眠”能调节昼夜节律吗？来自持续日常活动研究的证据。
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Circadian rhythms and their mechanisms.昼夜节律及其机制。
Experientia. 1986 Jan 15;42(1):1-13. doi: 10.1007/BF01975875.
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Metabolic rate: its circadian rhythmicity in the female domestic fowl.代谢率：雌性家禽的昼夜节律
J Physiol. 1978 Sep;282:419-27. doi: 10.1113/jphysiol.1978.sp012472.
J Clin Endocrinol Metab. 1963 Dec;23:1237-46. doi: 10.1210/jcem-23-12-1237.
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24 Hour periodicity and experimental medicine examples and interpretations.24小时周期性与实验医学实例及解读。
Postgrad Med. 1958 Oct;24(4):349-58. doi: 10.1080/00325481.1958.11692235.
5
Persisting circadian rhythm in hepatic glycogen of mice during inanition and dehydration.饥饿和脱水期间小鼠肝糖原中持续存在的昼夜节律
Experientia. 1966 Feb 15;22(2):113-4. doi: 10.1007/BF01900185.
6
The diurnal variation of plasma iron turnover and erythropoiesis in healthy subjects and cancer patients.健康受试者和癌症患者血浆铁周转率及红细胞生成的昼夜变化。
Br J Haematol. 1966 Sep;12(5):646-56. doi: 10.1111/j.1365-2141.1966.tb00148.x.
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[Circadian rhythm of serum-iron levels in children].[儿童血清铁水平的昼夜节律]
Dtsch Med Wochenschr. 1970 Jul 10;95(28):1476-83. doi: 10.1055/s-0028-1108671.
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Circadian rhythms in urinary light chains, serum iron and other variables of multiple myeloma patients.多发性骨髓瘤患者尿轻链、血清铁及其他变量的昼夜节律。
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Chronobiology and nutrition.时间生物学与营养
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Protection by timing treatment according to bodily rhythms - an analogy to protection by scrubbing before surgery.根据身体节律安排治疗时间进行保护——类似于手术前通过擦洗进行保护。
Chronobiologia. 1974 Sep;1 Suppl 1:27-72.