Chung S H, Heo S J, Koak J Y, Kim S K, Lee J B, Han J S, Han C H, Rhyu I C, Lee S J
Department of Prosthodontics and Dental Research Institute, College of Dentistry, Seoul National University, Korea.
J Oral Rehabil. 2008 Mar;35(3):229-36. doi: 10.1111/j.1365-2842.2006.01653.x.
The purpose of this study was to evaluate the geometry and surface characteristics of osseointegration after functional loading by radiographic, periodontal and histomorphometric analyses. We analysed three groups of implants with different geometry and surface characteristics using experimental dogs. The control group received Brånemark implants (group 1). Group 2 and group 3 implants each had a 0.5-mm pitch height but differed in surface characteristics. Group 2 implants were machine surfaced and group 3 implants were thermally oxidized at 800 degrees C for 2 h in a pure oxygen atmosphere. For these experiments, which used a total of four healthy beagle dogs, the implants were randomly installed into the extracted first, second and third premolar positions. The animals received radiographic and clinical periodontal examinations at 6 and 12 months post-loading, and were then killed for histomorphometric analysis. The radiographic analysis showed that mean crestal bone resorption in the control group was greater than that observed in the experimental groups (P < 0.05). The percentage of bone-to-implant contact for group 3 (83.7%) was significantly higher than in groups 1 (74.4%) and 2 (75.0%) (P < 0.05). Overall, implant geometry and surface treatment affected the rate of crestal bone resorption and bone healing surrounding the dental implants.
本研究的目的是通过影像学、牙周及组织形态计量学分析，评估功能负载后骨整合的几何形状和表面特征。我们使用实验犬分析了三组具有不同几何形状和表面特征的种植体。对照组接受Brånemark种植体（第1组）。第2组和第3组种植体的螺距高度均为0.5毫米，但表面特征不同。第2组种植体为机械加工表面，第3组种植体在纯氧气氛中于800摄氏度热氧化2小时。在这些实验中，总共使用了4只健康的比格犬，将种植体随机植入拔除的第一、第二和第三前磨牙位置。在负载后6个月和12个月对动物进行影像学和临床牙周检查，然后处死进行组织形态计量学分析。影像学分析表明，对照组的平均嵴顶骨吸收大于实验组（P < 0.05）。第3组的骨-种植体接触百分比（83.7%）显著高于第1组（74.4%）和第2组（75.0%）（P < 0.05）。总体而言，种植体的几何形状和表面处理影响了牙种植体周围嵴顶骨吸收和骨愈合的速率。
