Tran Ngoc Buu, Houben Rein M G J, Hoang Thi Quy, Nguyen Thi Ngoc Lan, Borgdorff Martien W, Cobelens Frank G J
Pham Ngoc Thach TB and Lung Disease Hospital, Ho Chi Minh City, Vietnam.
Emerg Infect Dis. 2007 Oct;13(10):1463-9. doi: 10.3201/eid1310.060774.
In Ho Chi Minh City, Vietnam, reporting rates for tuberculosis (TB) are rising in an emerging HIV epidemic. To describe the HIV epidemic among TB patients and quantify its impact on rates of reported TB, we performed a repeated cross-sectional survey from 1997 through 2002 in a randomly selected sample of inner city TB patients. We assessed effect by adjusting TB case reporting rates by the fraction of TB cases attributable to HIV infection. HIV prevalence in TB patients rose exponentially from 1.5% to 9.0% during the study period. Young (<35 years), single, male patients were mostly affected; injection drug use was a potent risk factor. After correction for HIV infection, the trend in TB reporting rates changed from a 1.9% increase to a 0.4% decrease per year. An emerging HIV epidemic, concentrated in young, male, injection drug users, is responsible for increased TB reporting rates in urban Vietnam.
在越南胡志明市,随着艾滋病病毒(HIV)疫情的出现,结核病(TB)报告率正在上升。为了描述结核病患者中的HIV疫情,并量化其对结核病报告率的影响,我们于1997年至2002年对市中心随机抽取的结核病患者样本进行了重复横断面调查。我们通过将结核病病例报告率按HIV感染所致结核病病例的比例进行调整来评估影响。在研究期间,结核病患者中的HIV患病率从1.5%呈指数增长至9.0%。年轻(<35岁)、单身男性患者受影响最大;注射吸毒是一个重要的危险因素。校正HIV感染后,结核病报告率的趋势从每年上升1.9%变为下降0.4%。集中在年轻男性注射吸毒者中的HIV疫情新情况,是越南城市结核病报告率上升的原因。