Ternovoi Vladimir A, Protopopova Elena V, Chausov Eugene V, Novikov Dmitry V, Leonova Galina N, Netesov Sergey V, Loktev Valery B
State Research Center of Virology and Biotechnology VECTOR, Koltsovo, Novosibirsk Region, Russia.
Emerg Infect Dis. 2007 Oct;13(10):1574-8. doi: 10.3201/eid1310.070158.
We isolated a novel strain of tickborne encephalitis virus (TBEV), Glubinnoe/2004, from a patient with a fatal case in Russia. We sequenced the strain, whose landmark features included 57 amino acid substitutions and 5 modified cleavage sites. Phylogenetically, Glubinnoe/2004 is a novel variant that belongs to the Eastern type of TBEV.
我们从俄罗斯一名死亡患者身上分离出一种新型蜱传脑炎病毒(TBEV)毒株,即格鲁比诺/2004毒株。我们对该毒株进行了测序,其标志性特征包括57个氨基酸替换和5个修饰的裂解位点。从系统发育角度来看,格鲁比诺/2004是一种属于TBEV东方型的新型变体。