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马尔堡病毒储存宿主的研究。

Studies of reservoir hosts for Marburg virus.

作者信息

Swanepoel Robert, Smit Sheilagh B, Rollin Pierre E, Formenty Pierre, Leman Patricia A, Kemp Alan, Burt Felicity J, Grobbelaar Antoinette A, Croft Janice, Bausch Daniel G, Zeller Hervé, Leirs Herwig, Braack L E O, Libande Modeste L, Zaki Sherif, Nichol Stuart T, Ksiazek Thomas G, Paweska Janusz T

机构信息

National Institute for Communicable Diseases, Sandringham, Republic of South Africa.

出版信息

Emerg Infect Dis. 2007 Dec;13(12):1847-51. doi: 10.3201/eid1312.071115.

DOI:10.3201/eid1312.071115
PMID:18258034
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2876776/
Abstract

To determine reservoir hosts for Marburg virus (MARV), we examined the fauna of a mine in northeastern Democratic Republic of the Congo. The mine was associated with a protracted outbreak of Marburg hemorrhagic fever during 1998-2000. We found MARV nucleic acid in 12 bats, comprising 3.0%-3.6% of 2 species of insectivorous bat and 1 species of fruit bat. We found antibody to the virus in the serum of 9.7% of 1 of the insectivorous species and in 20.5% of the fruit bat species, but attempts to isolate virus were unsuccessful.

摘要

为确定马尔堡病毒(MARV)的储存宿主,我们对刚果民主共和国东北部一座矿井的动物群落进行了调查。该矿井曾在1998年至2000年期间发生过持续的马尔堡出血热疫情。我们在12只蝙蝠体内发现了马尔堡病毒核酸,这些蝙蝠分属于2种食虫蝙蝠和1种果蝠,占这3种蝙蝠的3.0% - 3.6%。我们在其中1种食虫蝙蝠9.7%的血清样本以及20.5%的果蝠血清样本中发现了该病毒抗体,但病毒分离尝试未获成功。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/637c/2876776/2751f3792ad4/07-1115-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/637c/2876776/cba41da5d97a/07-1115-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/637c/2876776/2751f3792ad4/07-1115-F2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/637c/2876776/cba41da5d97a/07-1115-F1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/637c/2876776/2751f3792ad4/07-1115-F2.jpg

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