Fish M, Bayer A J, Gallacher J E J, Bell T, Pickering J, Pedro S, Dunstan F D, Ben-Shlomo Y, Ebrahim S
Department of Geriatric Medicine, Centre for Health Sciences Research, Cardiff University, Cardiff, UK.
Neuroepidemiology. 2008;30(1):25-33. doi: 10.1159/000115439. Epub 2008 Feb 6.
BACKGROUND/AIMS: The prevalence of dementia and cognitive impairment not dementia was investigated in the Caerphilly Prospective Study cohort (men currently aged 65-84 years).
Of 1,633 men eligible for cognitive screening, 1,225 (75%) were seen, with those failing the screening criteria (CAMCOG <83 or decline in CAMCOG >9) being neurologically examined.
For dementia, diagnosed by DSM-IV criteria, the population prevalence was 5.2% rising to 6.1% in the screened population. For cognitive impairment not dementia, the prevalence in the screened population was 15.6% giving an overall prevalence of cognitive impairment of 21.8%. Prevalence rose fivefold between ages of 65 and 84 years to reach over 50%.
These figures are likely to underestimate actual prevalence in this population, and developing effective interventions should be a public health priority.
背景/目的：在卡菲利前瞻性研究队列（目前年龄在65 - 84岁的男性）中调查痴呆症和非痴呆性认知障碍的患病率。
在1633名符合认知筛查条件的男性中，1225人（75%）接受了检查，未通过筛查标准（CAMCOG<83或CAMCOG下降>9）的人接受了神经学检查。
根据DSM-IV标准诊断的痴呆症，总体患病率为5.2%，在筛查人群中升至6.1%。对于非痴呆性认知障碍，筛查人群中的患病率为15.6%，认知障碍的总体患病率为21.8%。患病率在65岁至84岁之间增长了五倍，超过50%。
这些数字可能低估了该人群的实际患病率，制定有效的干预措施应成为公共卫生的优先事项。
