石楠中的两种新三萜类化合物。
Two new triterpenoids from Photinia serrulata.
作者信息
Song Yaling, Wang Yuehu, Lu Qing, Gao Jinming, Bi Minggang, Cheng Yongxian
机构信息
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China.
出版信息
Molecules. 2007 Dec 20;12(12):2599-604. doi: 10.3390/12122599.
Two new triterpenoids, 2alpha,3beta,11alpha,13beta-tetrahydroxy-12-ketooleanan-28-oic acid(1) and 3beta-hydroxy-12-keto-9(11)-ursen-28,13beta-olide (2) were isolated from the leaves ofPhotinia serrulata. Their structures were identified by spectral methods. Compounds 1 and2 were assessed for cytotoxic activity against three human tumor cell lines (A-549, HCT-8,and BEL-7402), and they showed no cytotoxic effects at concentrations up to 5microg/mL.
从石楠叶中分离得到两个新的三萜类化合物，2α,3β,11α,13β-四羟基-12-氧代齐墩果烷-28-酸（1）和3β-羟基-12-氧代-9(11)-乌苏烯-28,13β-内酯（2）。通过光谱方法鉴定了它们的结构。对化合物1和2针对三种人类肿瘤细胞系（A-549、HCT-8和BEL-7402）进行了细胞毒性活性评估，在浓度高达5μg/mL时它们未显示出细胞毒性作用。
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