Boutou Afroditi K, Tsiata Eleni A, Pataka Athanasia, Kontou Paschalina K, Pitsiou Georgia G, Argyropoulou Paraskevi
Respiratory Failure Unit, Aristotle University, G Papanikolaou Hospital, Thessaloniki, Greece.
Prim Care Respir J. 2008 Mar;17(1):32-8. doi: 10.3132/pcrj.2008.00009.
To identify the predictors of six-month continuous abstinence among Greek smokers treated in a Smoking Cessation Clinic, emphasising the role of sleep disturbance on the outcome.
A nested case-control design was used. Patients who attended the Smoking Cessation Clinic between November 2004 and October 2005, and who completed six months of follow-up, constituted the final study population (N=285). The patients were separated into two groups - those who managed to quit smoking and those who didn't. The cessation method included pharmacotherapy, one-to- one behavioral counselling, and follow-up by telephone communication.
Among various baseline characteristics examined, multivariate regression analysis indicated that the time to first cigarette after awakening, and use of bupropion, independently predicted abstinence, while awakening during the night was negatively associated with abstinence.
These multivariate factors, which can positively or negatively affect the outcome, should be taken into account so that smoking cessation treatment can be individualised.
确定在戒烟诊所接受治疗的希腊吸烟者六个月持续戒烟的预测因素，重点强调睡眠障碍对结果的作用。
采用巢式病例对照设计。2004年11月至2005年10月期间到戒烟诊所就诊并完成六个月随访的患者构成最终研究人群（N = 285）。患者被分为两组——成功戒烟者和未戒烟者。戒烟方法包括药物治疗、一对一行为咨询以及通过电话沟通进行随访。
在检查的各种基线特征中，多因素回归分析表明，醒来后至吸第一支烟的时间以及安非他酮的使用可独立预测戒烟情况，而夜间醒来与戒烟呈负相关。
这些可对结果产生积极或消极影响的多因素应予以考虑，以便戒烟治疗能够个体化。
