Ho Jau-Der, Tsai Ching-Yao, Liou Shiow-Wen, Tsai Ray Jui-Fang, Lin Herng-Ching
Department of Ophthalmology, Taipei Medical University Hospital, Taipei, Taiwan.
Am J Ophthalmol. 2008 Apr;145(4):722-728. doi: 10.1016/j.ajo.2007.12.017. Epub 2008 Feb 11.
To determine whether seasonal variation exists in the incidence of retinal vein occlusion.
Retrospective, nationwide population-based administrative database study.
We collected data on outpatient and emergency visits for the period from January 1999 through December 2003 from the Taiwan National Health Insurance Research Database, a source that covers more than 96% of Taiwan's 23 million citizens. In total, 20,792 patients with a first-time diagnosis of either central retinal vein occlusion or branch retinal vein occlusion (The International Classification of Disease, Ninth Revision, Clinical Modification [ICD-9-CM] code 362.35 or 362.36, respectively) were identified. Monthly incidence of retinal vein occlusion was obtained for each age group, each gender group, and for the entire sample. The autoregressive integrated moving average method of analysis was adopted to examine seasonality in the monthly incidence of retinal vein occlusion.
The monthly incidence rates of retinal vein occlusion revealed significant seasonality, with a clear peak in January for each age group and each gender group, as well as for the total sample.
Our study demonstrates significant seasonal variations in the retinal vein occlusion incidence, with the peak occurrence in the winter month of January.
确定视网膜静脉阻塞的发病率是否存在季节性变化。
基于全国人口的回顾性行政数据库研究。
我们从台湾全民健康保险研究数据库收集了1999年1月至2003年12月期间的门诊和急诊就诊数据，该数据库覆盖了台湾2300万公民中的96%以上。总共识别出20792例首次诊断为视网膜中央静脉阻塞或视网膜分支静脉阻塞的患者（国际疾病分类第九版临床修订本[ICD-9-CM]代码分别为362.35或362.36）。获取了每个年龄组、每个性别组以及整个样本的视网膜静脉阻塞月发病率。采用自回归积分滑动平均分析方法来检验视网膜静脉阻塞月发病率的季节性。
视网膜静脉阻塞的月发病率显示出显著的季节性，每个年龄组、每个性别组以及整个样本在1月份均有明显的峰值。
我们的研究表明视网膜静脉阻塞发病率存在显著的季节性变化，发病高峰出现在冬季的1月份。
