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精神分裂症遗传风险高低的被收养者及其养父母交流变异程度低的情况下,明尼苏达多项人格测验的稳定性。

Stability in MMPI among adoptees with high and low genetic risk for schizophrenia and with low Communication Deviance of their adoptive parents.

机构信息

Department of Psychiatry, Institute of Clinical Medicine, University of Oulu, Box 5000, FI-90014, Finland.

出版信息

Psychiatry Res. 2013 Nov 30;210(1):69-74. doi: 10.1016/j.psychres.2013.05.021. Epub 2013 Jun 14.

Abstract

Stability has been considered an important aspect of vulnerability to schizophrenia. The temporal stability of the scales in the Minnesota Multiphasic Personality Inventory (MMPI) was examined, using adoptees from the Finnish Adoptive Family Study of Schizophrenia. Adoptees who were high-risk (HR) offspring of biological mothers having a schizophrenia spectrum disorder (n=28) and low-risk (LR) controls (n=46) were evaluated using 15 MMPI scales at the initial assessment (HR, mean age 24 years; LR, mean age 23 years) and at the follow-up assessment after a mean interval of 11 years. Stability of the MMPI scales was also assessed in the groups of adoptees, assigned according to the adoptive parents'(n=44) communication style using Communication Deviance (CD) scale as an environmental factor. Initial Lie, Frequency, Correction, Psychopathic Deviate, Schizophrenia, Manifest Hostility, Hypomania, Phobias, Psychoticism, Religious Fundamentalism, Social Maladjustment, Paranoid Schizophrenia, Golden-Meehl Indicators, Schizophrenia Proneness and 8-6 scale scores significantly predicted the MMPI scores at the follow-up assessment indicating stability in the characteristics of thinking, affective expression, social relatedness and volition. Low CD in the family had an effect on the stabilization of personality traits such as social withdrawal and restricted affectivity assessed by Correction and Hostility.

摘要

稳定性被认为是易患精神分裂症的一个重要方面。本研究使用芬兰精神分裂症收养家庭研究中的被收养者,考察明尼苏达多相人格问卷(MMPI)各分量表的时间稳定性。高风险(HR)组为亲生母亲患有精神分裂谱系障碍的生物学后代(n=28),低风险(LR)对照组(n=46),采用 15 个 MMPI 分量表进行评估,在初始评估时(HR,平均年龄 24 岁;LR,平均年龄 23 岁)和 11 年后的随访评估中进行评估。根据收养父母的沟通方式(n=44),使用沟通偏差(CD)量表作为环境因素,对被收养者进行分组,评估 MMPI 量表的稳定性。最初的 Lie、Frequency、Correction、Psychopathic Deviate、Schizophrenia、Manifest Hostility、Hypomania、Phobias、Psychoticism、Religious Fundamentalism、Social Maladjustment、Paranoid Schizophrenia、Golden-Meehl Indicators、Schizophrenia Proneness 和 8-6 量表分数在随访评估中显著预测 MMPI 分数,表明思维、情感表达、社会关系和意志等特征的稳定性。家庭中 CD 较低会影响人格特质的稳定,如由 Correction 和 Hostility 评估的社交退缩和受限的情感表达。

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