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雄激素合成代谢类固醇也会损害右心室功能。

Androgenic anabolic steroids also impair right ventricular function.

作者信息

Kasikcioglu Erdem, Oflaz Huseyin, Umman Berrin, Bugra Zehra

出版信息

Int J Cardiol. 2009 May 1;134(1):123-5. doi: 10.1016/j.ijcard.2007.12.027. Epub 2008 Feb 12.

Abstract

Chronic anabolic steroid use suppresses left ventricular functions. However, there is no information regarding the chronic effects of anabolic steroids on right ventricular function which also plays a key role in global cardiac function. The main objective of the present study was to investigate the effects of androgenic anabolic steroids usage among athletes on remodeling the right part of the heart. Androgenic-anabolic steroids-using bodybuilders had smaller diastolic velocities of both ventricles than drug-free bodybuilders and sedentary counterparts. This study shows that androgenic anabolic steroids-using bodybuilders exhibited depressed diastolic functions of both ventricles.

摘要

长期使用合成代谢类固醇会抑制左心室功能。然而,关于合成代谢类固醇对右心室功能的长期影响尚无相关信息,而右心室功能在整体心脏功能中也起着关键作用。本研究的主要目的是调查运动员使用雄激素合成代谢类固醇对心脏右部重塑的影响。使用雄激素合成代谢类固醇的健美运动员的两个心室舒张速度均低于不使用药物的健美运动员和久坐不动的对照组。这项研究表明,使用雄激素合成代谢类固醇的健美运动员的两个心室舒张功能均受到抑制。

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