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生物医学应用中电阻抗断层成像的频分复用

Frequency-division multiplexing for electrical impedance tomography in biomedical applications.

作者信息

Granot Yair, Ivorra Antoni, Rubinsky Boris

机构信息

School of Computer Science and Engineering, Hebrew University of Jerusalem, 78b Ross Building, Jerusalem 91904, Israel.

出版信息

Int J Biomed Imaging. 2007;2007:54798. doi: 10.1155/2007/54798.

Abstract

Electrical impedance tomography (EIT) produces an image of the electrical impedance distribution of tissues in the body, using electrodes that are placed on the periphery of the imaged area. These electrodes inject currents and measure voltages and from these data, the impedance can be computed. Traditional EIT systems usually inject current patterns in a serial manner which means that the impedance is computed from data collected at slightly different times. It is usually also a time-consuming process. In this paper, we propose a method for collecting data concurrently from all of the current patterns in biomedical applications of EIT. This is achieved by injecting current through all of the current injecting electrodes simultaneously, and measuring all of the resulting voltages at once. The signals from various current injecting electrodes are separated by injecting different frequencies through each electrode. This is called frequency-division multiplexing (FDM). At the voltage measurement electrodes, the voltage related to each current injecting electrode is isolated by using Fourier decomposition. In biomedical applications, using different frequencies has important implications due to dispersions as the tissue's electrical properties change with frequency. Another significant issue arises when we are recording data in a dynamic environment where the properties change very fast. This method allows simultaneous measurements of all the current patterns, which may be important in applications where the tissue changes occur in the same time scale as the measurement. We discuss the FDM EIT method from the biomedical point of view and show results obtained with a simple experimental system.

摘要

电阻抗断层成像(EIT)利用放置在成像区域周边的电极生成人体组织电阻抗分布的图像。这些电极注入电流并测量电压,根据这些数据可以计算出阻抗。传统的EIT系统通常以串行方式注入电流模式,这意味着阻抗是根据在稍有不同时间收集的数据计算得出的。这通常也是一个耗时的过程。在本文中,我们提出了一种在EIT的生物医学应用中从所有电流模式同时采集数据的方法。这是通过同时向所有电流注入电极注入电流,并一次性测量所有产生的电压来实现的。通过向每个电极注入不同频率的电流来分离来自各个电流注入电极的信号。这被称为频分复用(FDM)。在电压测量电极处,利用傅里叶分解来隔离与每个电流注入电极相关的电压。在生物医学应用中,由于组织的电学特性随频率变化而存在色散,使用不同频率具有重要意义。当我们在动态环境中记录数据时,另一个重大问题就会出现,在这种环境中特性变化非常快。这种方法允许同时测量所有电流模式,这在组织变化与测量处于相同时间尺度的应用中可能很重要。我们从生物医学的角度讨论了FDM EIT方法,并展示了用一个简单实验系统获得的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4b6/2211417/d0bf72c09b06/IJBI2007-54798.009.jpg

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