Discipline of Pharmacology & Therapeutics, NUI, Galway, Ireland.
Department of Surgical, Oncological and Gastroenterological Sciences, University of Padua, Italy.
J Crohns Colitis. 2014 Jan;8(1):19-30. doi: 10.1016/j.crohns.2013.04.009. Epub 2013 May 7.
Patients with inflammatory bowel diseases (IBD) have an excess risk of certain gastrointestinal cancers. Much work has focused on colon cancer in IBD patients, but comparatively less is known about other more rare cancers. The European Crohn's and Colitis Organization established a pathogenesis workshop to review what is known about these cancers and formulate proposals for future studies to address the most important knowledge gaps. This article reviews the current state of knowledge about small bowel adenocarcinoma, ileo-anal pouch and rectal cuff cancer, and anal/perianal fistula cancers in IBD patients.
炎症性肠病（IBD）患者存在某些胃肠道癌症的高发风险。大量研究集中在 IBD 患者的结肠癌上，但对其他更罕见的癌症知之甚少。欧洲克罗恩病和结肠炎组织成立了一个发病机制研讨会，旨在回顾关于这些癌症的已知信息，并提出未来研究的建议，以解决最重要的知识空白。本文综述了 IBD 患者的小肠腺癌、回肠肛管吻合术和直肠套叠癌以及肛门/肛周瘘管癌的现有知识状况。
