Mamitsuka Hiroshi
Bioinformatics Center, Institute for Chemical Research, Kyoto University, Gokasho, Uji 611-0011, Japan.
Drug Discov Today. 2008 Feb;13(3-4):118-23. doi: 10.1016/j.drudis.2007.10.013. Epub 2007 Nov 26.
The recent development and applications of tree-based informatics on glycans have accelerated the biological analysis on glycans, particularly from structural viewpoints. We review three major aspects of recent informatics innovations on glycan structures: maturity of well-organized databases on glycan structures linking with other biological information, implementation of glycan structure matching algorithms and extensive development of methods for mining frequent patterns from glycan structures.
基于树的聚糖信息学的最新发展与应用加速了聚糖的生物学分析，特别是从结构角度。我们综述了聚糖结构信息学创新的三个主要方面：与其他生物信息相联系的、组织良好的聚糖结构数据库的成熟度；聚糖结构匹配算法的实施；以及从聚糖结构中挖掘频繁模式的方法的广泛发展。
