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[巴西南部一个城市药物急性中毒的原因]

[Causes of acute poisoning with medication in a southern Brazilian city].

作者信息

Margonato Fabiana Burdini, Thomson Zuleika, Paoliello Mônica Maria Bastos

机构信息

Centro de Ciências da Saúde, Universidade Estadual de Londrina, Londrina, Brasil.

出版信息

Cad Saude Publica. 2008 Feb;24(2):333-41. doi: 10.1590/s0102-311x2008000200012.

DOI:10.1590/s0102-311x2008000200012
PMID:18278280
Abstract

Acute poisoning with medicines in Brazil has various causes, including a deficient national drug policy. The current study thus aimed to analyze socioeconomic variables, prescription characteristics, and forms of purchase or acquisition and storing of medicines by victims of acute unintentional poisoning. The data were collected during home visits to patients with a record of acute unintentional drug poisoning according to the Poison Control Center in Maringá, Paraná State, in 2004. The variables were related to the victim, the poisoning event, the product, and its household storage. For the 97 poisonings recorded during the study period, 72 families were interviewed, with the majority of the victims under 10 years of age (73.6%), males (54.2%), and from lower-income groups (63.9%). Many interviewees reported not having received information about the drug (76.5%). There was a significant association between lower-income status and inadequate drug storage (p < 0.05). A larger proportion of poisonings in higher-income families involved expired products (p < 0.05). Inadequate acquisition and storage of drugs may thus have facilitated the occurrence of poisonings.

摘要

在巴西,药物急性中毒有多种原因,包括国家药物政策不完善。因此,本研究旨在分析急性非故意中毒受害者的社会经济变量、处方特征以及药品的购买、获取和储存方式。2004年,研究人员在巴拉那州马林加市的中毒控制中心对有急性非故意药物中毒记录的患者进行家访时收集了相关数据。这些变量与受害者、中毒事件、产品及其家庭储存情况有关。在研究期间记录的97起中毒事件中,对72个家庭进行了访谈,大多数受害者年龄在10岁以下(73.6%),男性(54.2%),来自低收入群体(63.9%)。许多受访者表示未收到有关该药物的信息(76.5%)。低收入状况与药品储存不当之间存在显著关联(p<0.05)。高收入家庭中较大比例的中毒事件涉及过期产品(p<0.05)。因此,药品获取和储存不当可能助长了中毒事件的发生。

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