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约旦医药制剂所致急性中毒事件的回顾性评估:来自 Pharmacy One™ 中毒咨询中心的数据,2014 年至 2018 年-第二部分。

Retrospective assessment of acute poisoning incidents by pharmaceutical agents in Jordan: Data from Pharmacy One™ Poison Call Center, 2014 to 2018-Part II.

机构信息

Department of Pharmacy Practice, Faculty of Pharmacy, Yarmouk University, Irbid, Jordan.

Department of Pharmaceutical sciences, Faculty of Pharmacy, Yarmouk University, Irbid, Jordan.

出版信息

Pharmacol Res Perspect. 2020 Apr;8(2):e00583. doi: 10.1002/prp2.583.

DOI:10.1002/prp2.583
PMID:32302066
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7164419/
Abstract

Poison control centers provide surveillance data that can be used to estimate the magnitude of poisoning cases and the level of public awareness and to evaluate control measures. The aim of this study is to describe the drug-related poisoning queries received by the Pharmacy One™ Poisoning Call Center (P PCC) in Jordan. This is a retrospective descriptive study of the acute drug-related poisoning incidents in the Jordanian population recorded by the P PCC during the 2014-2018 period. The inquiries received were recorded on a predesigned form. The demographic data, including the age and the sex of the patient, the route of and reason for exposure and the drug therapeutic groups, in addition to medical outcomes, were extracted utilizing computerized Oracle and Excel spreadsheets. During the period of evaluation, 900 drug-related poisoning incidents were reported to the P PCC. The majority of calls (48.5%) were received via 911, followed by the public (48.56%) and healthcare professionals (27.1%). More than half of the poisoning incidents were recorded among males (52.5%). Adults were the most affected group (40.5%), followed by children (34.0%). Unintentional exposure was the most common cause of poisoning (58.6%), followed by suicide attempts (25.3%). Nonsteroidal anti-inflammatory drugs and paracetamol caused the majority of the reported cases. Poisoning incidents were mainly classified as mild to moderate (56.1%), while only 16.6% were severe. The P PCC has demonstrated an important and vital role in improving patient safety and providing education on rational drug use. Reflections on these data can be used to increase public awareness in promoting the rational use of medications among Jordanian citizens.

摘要

中毒控制中心提供监测数据,可用于估计中毒病例的严重程度和公众意识水平,并评估控制措施。本研究旨在描述 2014-2018 年期间 Pharmacy One ™ 中毒呼叫中心(PPCC)在约旦收到的与药物相关的中毒咨询。这是一项对 PPCC 在约旦记录的急性与药物相关的中毒事件的回顾性描述性研究。通过预先设计的表格记录收到的咨询。利用计算机化的 Oracle 和 Excel 电子表格提取人口统计学数据,包括患者的年龄和性别、暴露途径和原因以及药物治疗组,以及医疗结果。在评估期间,向 PPCC 报告了 900 起与药物相关的中毒事件。大多数电话(48.5%)通过 911 收到,其次是公众(48.56%)和医疗保健专业人员(27.1%)。超过一半的中毒事件发生在男性(52.5%)中。成年人是受影响最大的群体(40.5%),其次是儿童(34.0%)。意外暴露是中毒的最常见原因(58.6%),其次是自杀企图(25.3%)。非甾体抗炎药和对乙酰氨基酚引起了大多数报告的病例。中毒事件主要被归类为轻度至中度(56.1%),而只有 16.6%是严重的。PPCC 在提高患者安全性和提供合理用药教育方面发挥了重要作用。对这些数据的反思可以用来提高公众意识,促进约旦公民合理使用药物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7067/7164419/dc4684fd8cc5/PRP2-8-e00583-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7067/7164419/de9dcdfb5308/PRP2-8-e00583-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7067/7164419/0c71029ecf5a/PRP2-8-e00583-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7067/7164419/dc4684fd8cc5/PRP2-8-e00583-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7067/7164419/de9dcdfb5308/PRP2-8-e00583-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7067/7164419/0c71029ecf5a/PRP2-8-e00583-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7067/7164419/dc4684fd8cc5/PRP2-8-e00583-g003.jpg

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